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Details

Stereochemistry ACHIRAL
Molecular Formula C8H18N2O4S
Molecular Weight 238.305
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID

SMILES

OCCN1CCN(CCS(O)(=O)=O)CC1

InChI

InChIKey=JKMHFZQWWAIEOD-UHFFFAOYSA-N
InChI=1S/C8H18N2O4S/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14/h11H,1-8H2,(H,12,13,14)

HIDE SMILES / InChI

Molecular Formula C8H18N2O4S
Molecular Weight 238.305
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

HYDROXYETHYLPIPERAZINE ETHANE SULFONIC ACID (wider known as HEPES), a zwitterionic buffering agent, is one of the best all-purpose buffers available for use in biological research. HEPES is most effective as a buffer at pH 6.0 to 8.5. It was shown that HEPES could be taken into account as simple and efficient reagent for promoting protein transfection and intracellular targeting and had the potential for myriad clinical applications.

Approval Year

PubMed

Substance Class Chemical
Record UNII
RWW266YE9I
Record Status Validated (UNII)
Record Version