POTASSIUM

Possibly Marketed Outside US

Details

Stereochemistry	ACHIRAL
Molecular Formula	K
Molecular Weight	39.0983
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[K]

InChI

InChIKey=NTTOTNSKUYCDAV-UHFFFAOYSA-N

InChI=1S/K.H

HIDE SMILES / InChI

Molecular Formula	K
Molecular Weight	39.0983
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Studies on digitalis-induced arrhythmias in glucose- and insulin-induced hypokalemia.	1977 Jun	140932
The role of cell swelling in the stimulation of glycogen synthesis by insulin.	1992 Mar 15	1554362
Life-threatening hyperkalaemia in an elderly patient receiving captopril, furosemide (frusemide) and potassium supplements.	1992 Mar-Apr	1605901
Potassium supplementation in lithium patients: a timely intervention or premature speculation?	1992 Oct	1429477
Familial hypomagnesemia--hypercalciuria and pseudotumor cerebri.	2001	15503623
Glycosphingolipids modulate renal phosphate transport in potassium deficiency.	2001 Aug	11473652
Does acetaldehyde mediate ethanol action in the central nervous system?	2001 Nov	11707631
Evidence supporting a role for KCl cotransporter in the thick ascending limb of Henle's loop.	2001 Nov	11703599
IP(3) receptor function and localization in myotubes: an unexplored Ca(2+) signaling pathway in skeletal muscle.	2001 Oct	11707519
Five novel single nucleotide polymorphisms in the CYP2C8 gene, one of which induces a frame-shift.	2002	15618689
Activation of Na+/K+-ATPase by the serum and glucocorticoid-dependent kinase isoforms.	2002	12590200
Purification and characterization of cytosolic glycerol-3-phosphate dehydrogenase from skeletal muscle of jerboa (Jaculus orientalis).	2002 Feb	11952153
Cloning of rabbit Kir6.1, SUR2A, and SUR2B: possible candidates for a renal K(ATP) channel.	2002 Feb	11788443
Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3.	2002 Feb 1	11826162
Cocaine induced hypokalaemic periodic paralysis.	2002 Jul	12082066
Inhibitory effects of opioids on voltage-dependent Ca(2+) channels and catecholamine secretion in cultured porcine adrenal chromaffin cells.	2002 Jun 28	12031848
Fenamate-induced enhancement of heterologously expressed HERG currents in Xenopus oocytes.	2002 Oct 11	12359267
Calmodulin-dependent kinase I regulates adrenal cell expression of aldosterone synthase.	2002 Sep	12193581
Differential sensitivity of inward rectifier K+ channels to metabolic inhibitors.	2002 Sep 27	12118013
Ammonia prevents glutamate-induced but not low K(+)-induced apoptosis in cerebellar neurons in culture.	2003	12654341
Inactivation of aconitase during the apoptosis of mouse cerebellar granule neurons induced by a deprivation of membrane depolarization.	2003 Feb 15	12548706
A novel two-pore domain K+ channel, TRESK, is localized in the spinal cord.	2003 Jul 25	12754259
Plasticity of KIR channels in human smooth muscle cells from internal thoracic artery.	2003 Jun	12598232
Inhibition of G protein-activated inwardly rectifying K+ channels by fluoxetine (Prozac).	2003 Mar	12684268
Functional identification of ion binding sites at the internal end of the pore in Shaker K+ channels.	2003 May 15	12665608
Effects of truncated angiotensins in humans after double blockade of the renin system.	2003 Nov	12869368
[Production of aldosterone by rat mesangial cell and the accumulation of extracellular matrix induced by aldosterone].	2003 Nov 10	14642076
Involvement of transient receptor potential-like channels in responses to mGluR-I activation in midbrain dopamine neurons.	2003 Oct	14622174
Allosteric modulation of a neuronal K+ channel by 1-alkanols is linked to a key residue in the activation gate.	2003 Oct	12958027
Classification and rescue of ROMK mutations underlying hyperprostaglandin E syndrome/antenatal Bartter syndrome.	2003 Sep	12911542
Molecular features of an alcohol binding site in a neuronal potassium channel.	2003 Sep 30	14503874
The effect of cations on the amidase activity of human tissue kallikrein: 1-linear competitive inhibition by sodium, potassium, calcium and magnesium. 2-linear mixed inhibition by aluminium.	2004 Aug	15558947
The renal-specific transporter mediates facilitative transport of organic anions at the brush border membrane of mouse renal tubules.	2004 Aug	15284287
Activation of cardiac human ether-a-go-go related gene potassium currents is regulated by alpha(1A)-adrenoceptors.	2004 Dec	15365637
Differential effects of CB1 and opioid agonists on two populations of adult rat dorsal root ganglion neurons.	2004 Feb 18	14973253
Predictors of in-hospital ventricular fibrillation or torsades de pointes in patients with acute symptomatic bradycardia.	2004 Jan	15132370
Is postural tremor size controlled by interstitial potassium concentration in muscle?	2004 Jul	15201362
4-Chloro-benzo[F]isoquinoline (CBIQ) activates CFTR chloride channels and KCNN4 potassium channels in Calu-3 human airway epithelial cells.	2004 Jun	15148241
ET-1 inhibits B-16 murine melanoma cell migration by decreasing K(+) currents.	2004 Jun	15083534
Melatonin receptor agonist 2-iodomelatonin prevents apoptosis of cerebellar granule neurons via K(+) current inhibition.	2004 Mar	14962062
Additional repression of activity-dependent c-fos and BDNF mRNA expression by lipophilic compounds accompanying a decrease in Ca2+ influx into neurons.	2005 Jan	15527870
Monovalent cation leaks in human red cells caused by single amino-acid substitutions in the transport domain of the band 3 chloride-bicarbonate exchanger, AE1.	2005 Nov	16227998
Functional expression of Kir2.x in human aortic endothelial cells: the dominant role of Kir2.2.	2005 Nov	15958527
TASK-like K+ channels mediate effects of 5-HT and extracellular pH in rat dorsal vagal neurones in vitro.	2005 Oct 1	16020457
Erectile dysfunction in mice lacking the large-conductance calcium-activated potassium (BK) channel.	2005 Sep 1	16020453
Clinical evaluation of adverse effects during bepridil administration for atrial fibrillation and flutter.	2006 Jun	16723784
Functional expression of the TRPM4 cationic current in ventricular cardiomyocytes from spontaneously hypertensive rats.	2006 Oct	16966582
Adaptive downregulation of a quinidine-sensitive cation conductance in renal principal cells of TWIK-1 knockout mice.	2006 Oct	16847696
Hypokalemic rhabdomyolysis in a child due to amphotericin B therapy.	2007 Feb	16906399
TRPM4, a Ca2+-activated nonselective cation channel in mouse sino-atrial node cells.	2007 Feb 1	17188667

Patents

Substance Class	Chemical Created by `admin` on `Fri Jun 25 22:44:10 UTC 2021` Edited by `admin` on `Fri Jun 25 22:44:10 UTC 2021`
Record UNII	RWP5GA015D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

POTASSIUM

Systematic Name

English

POTASSIUM [MI]

Common Name

English

POTASSIUM [WHO-DD]

Common Name

English

POTASSIUM, METAL

Common Name

English

POTASSIUM [VANDF]

Common Name

English

POTASSIUM [HSDB]

Common Name

English

POTASSIUM METAL

Common Name

English

Common Name

English

POTASSIUM, ELEMENTAL

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 176.170