Approval Year
Substance Class |
Protein
Created
by
admin
on
Edited
Sat Dec 16 12:04:17 GMT 2023
by
admin
on
Sat Dec 16 12:04:17 GMT 2023
|
Protein Sub Type | |
Sequence Origin | HUMAN |
Sequence Type | COMPLETE |
Record UNII |
RV2QAE6UDF
|
Record Status |
Validated (UNII)
|
Record Version |
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-
Download
Name | Type | Language | ||
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Common Name | English | ||
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Common Name | English |
Code System | Code | Type | Description | ||
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RV2QAE6UDF
Created by
admin on Sat Dec 16 12:04:19 GMT 2023 , Edited by admin on Sat Dec 16 12:04:19 GMT 2023
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PRIMARY | |||
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Q92769
Created by
admin on Sat Dec 16 12:04:19 GMT 2023 , Edited by admin on Sat Dec 16 12:04:19 GMT 2023
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PRIMARY |
Related Record | Type | Details | ||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
Abexinostat (PCI-24781) is a modestly potent inhibitor to HDAC2. Phase 1/2.
INHIBITOR
MODERATE
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
IN-VIVO
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET |
Potent HDAC2 inhibitor in a cell-free assay.
INHIBITOR
IC50
|
||
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
Enzymatic Inhibition
IC50
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WEAK INHIBITOR->TARGET |
IC50
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
4SC-202 is a selective class I HDAC inhibitor and also displays inhibitory activity against Lysine specific demethylase 1 (LSD1). Phase 1.
INHIBITOR
IC50
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INHIBITOR -> TARGET |
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INHIBITOR -> TARGET | |||
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INHIBITOR -> TARGET |
CUDC-907 is a dual PI3K.ALPHA. and HDAC2 inhibitor. Phase 1.
INHIBITOR
IC50
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TARGET -> INHIBITOR | |||
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INHIBITOR -> TARGET |
Mocetinostat (MGCD0103) is a potent HDAC inhibitor with a 2- to 10- fold selectivity against HDAC2. Phase 2.
INHIBITOR
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Name | Property Type | Amount | Referenced Substance | Defining | Parameters | References |
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MOL_WEIGHT | CHEMICAL |
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