OREMEPERMIN ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:47:04 GMT 2025` Edited by `admin` on `Wed Apr 02 10:47:04 GMT 2025`
Protein Type	GROWTH FACTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	RS6ZQ4QBJ2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Hepatocyte growth factor KP-100 (recombinant human), (32-161)-(167-494)-? chain, (451?110') disulfide with ? chain

Preferred Name

English

OREMEPERMIN ALFA

Official Name

English

KP-100

Code

English

HUMAN HEPATOCYTE GROWTH FACTOR RECOMBINANT

Common Name

English

OREMEPERMIN ALFA [USAN]

Common Name

English

oremepermin alfa [INN]

Common Name

English

KP100

Code

English

human hepatocyte growth factor isoform 3 (HGF3, hepatopoietin A isoform 3, five amino acid-deleted variant of hepatocyte growth factor, dHGF), heterodimer (alpha and beta chains), glycosylated, produced in Chinese hamster ovary (CHO) cells; hepatocyte gr

Common Name

English

Code System Code Type Description

FDA UNII

RS6ZQ4QBJ2

Created by admin on Wed Apr 02 10:47:04 GMT 2025 , Edited by admin on Wed Apr 02 10:47:04 GMT 2025

PRIMARY

INN

11618

Created by admin on Wed Apr 02 10:47:04 GMT 2025 , Edited by admin on Wed Apr 02 10:47:04 GMT 2025

PRIMARY

INN

CAS

2396744-46-8

Created by admin on Wed Apr 02 10:47:04 GMT 2025 , Edited by admin on Wed Apr 02 10:47:04 GMT 2025

PRIMARY

SMS_ID

300000029734

Created by admin on Wed Apr 02 10:47:04 GMT 2025 , Edited by admin on Wed Apr 02 10:47:04 GMT 2025

PRIMARY

USAN

KL-73

Created by admin on Wed Apr 02 10:47:04 GMT 2025 , Edited by admin on Wed Apr 02 10:47:04 GMT 2025

PRIMARY

NCI_THESAURUS

C179111

Created by admin on Wed Apr 02 10:47:04 GMT 2025 , Edited by admin on Wed Apr 02 10:47:04 GMT 2025

PRIMARY

From	To
1_318	1_341
1_355	1_433
1_376	1_416
1_404	1_428
1_451	2_110
2_175	2_203
2_148	2_164
2_118	2_185
2_25	2_41
1_269	1_347
1_224	1_247
1_290	1_329
1_196	1_235
1_175	1_252
1_141	1_165
1_118	1_153
1_97	1_170
1_43	1_53
1_39	1_65

Linkage Type	Residue Index

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_258
N	1_366
N	2_72
N	2_159
O	1_440

Related Record Type Details


					XT5T3BT4QP

INHIBITOR -> TARGET

Amount:

Related Record Type Details


					RS6ZQ4QBJ2

OREMEPERMIN ALFA

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL