1,2-DICHLOROPROPANE

Details

Stereochemistry	RACEMIC
Molecular Formula	C3H6Cl2
Molecular Weight	112.986
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(Cl)CCl

InChI

InChIKey=KNKRKFALVUDBJE-UHFFFAOYSA-N

InChI=1S/C3H6Cl2/c1-3(5)2-4/h3H,2H2,1H3

HIDE SMILES / InChI

Molecular Formula	C3H6Cl2
Molecular Weight	112.986
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

PubMed

Title	Date	PubMed
Toxicity in man due to stain removers containing 1,2-dichloropropane.	1985 Nov	4063220
[Disseminated intravascular coagulation (DIC) caused by 1,2-dichloropropane (commercial trielin). Description of 2 cases].	1985 Sep-Oct	4088123
[Behavior of the excretion of mercapturic acid after administration of 1,2-dichloropropane to the rat].	1988 Jan-Feb	3173224
Oral toxicity of 1,2-dichloropropane: acute, short-term, and long-term studies in rats.	1989 May	2744274
1,2-Dichloropropane (DCP) toxicity is correlated with DCP-induced glutathione (GSH) depletion and is modulated by factors affecting intracellular GSH.	1990	1980407
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects.	1991 Mar-Apr	1664256
Purification, cloning, and sequencing of an enzyme mediating the reductive dechlorination of tetrachloroethylene (PCE) from Clostridium bifermentans DPH-1.	2001 May	11400736
Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition.	2002 Apr 16	11939779
Temperature dependence of Henry's law constant in an extended temperature range.	2002 Aug	12201206
Microbial structure of an anaerobic bioreactor population that continuously dechlorinates 1,2-dichloropropane.	2002 Mar 1	19709202
Acute renal and hepatic failure due to accidental percutaneous absorption of 1,2-dichlorpropane contained in a commercial paint fixative.	2003 Jan	12480995
Application of Fenton's reagent to regenerate activated carbon saturated with organochloro compounds.	2003 Mar	12531711
Adsorption from aqueous solutions of chlorinated organic compounds onto activated carbons.	2003 Sep 15	12962661
Metabolism and mutagenicity of source water contaminants 1,3-dichloropropane and 2,2-dichloropropane.	2004 Jan	14709629
The role of syntrophic associations in sustaining anaerobic mineralization of chlorinated organic compounds.	2005 Mar	15743720
Volatile organic compounds and pulmonary function in the Third National Health and Nutrition Examination Survey, 1988-1994.	2006 Aug	16882527
Distribution of volatile organic compounds in Sicilian groundwaters analysed by head space-solid phase micro extraction coupled with gas chromatography mass spectrometry (SPME/GC/MS).	2008 Aug	18703213
Affinity-based elimination of aromatic VOCs by highly crystalline multi-walled carbon nanotubes.	2008 Feb 15	18371779
Isolation of novel bacteria within the Chloroflexi capable of reductive dechlorination of 1,2,3-trichloropropane.	2009 Apr	19396942
Characterization of the chronic risk and hazard of hazardous air pollutants in the United States using ambient monitoring data.	2009 May	19479023
Dehalogenimonas lykanthroporepellens gen. nov., sp. nov., a reductively dehalogenating bacterium isolated from chlorinated solvent-contaminated groundwater.	2009 Nov	19625421
Stable carbon isotope fractionation of 1,2-dichloropropane during dichloroelimination by Dehalococcoides populations.	2009 Sep 15	19806720
Comments on "Degradation of 1,2,3-trichloropropane (TCP): hydrolysis, elimination, and reduction by iron and zinc".	2010 Apr 15	20192163
Degradation of 1,2,3-trichloropropane (TCP): hydrolysis, elimination, and reduction by iron and zinc.	2010 Jan 15	20000732
Inhalation carcinogenicity and toxicity of 1,2-dichloropropane in rats.	2010 Nov	21070183
Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-Dichloropropane in Male Syrian Hamsters and B6C3F1 Mice.	2015 May	25711234

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:14:32 UTC 2023` Edited by `admin` on `Fri Dec 15 19:14:32 UTC 2023`
Record UNII	RRZ023OFWL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,2-DICHLOROPROPANE

Systematic Name

English

NSC-1237

Code

English

1,2-DICHLOROPROPANE [IARC]

Common Name

English

DICHLOROPROPANE [MART.]

Common Name

English

PROPYLENE DICHLORIDE [MI]

Common Name

English

(±)-1,2-DICHLOROPROPANE

Systematic Name

English

1,2-DICHLOROPROPANE [ISO]

Common Name

English

1,2-DICHLOROPROPANE [HSDB]

Common Name

English

DICHLOROPROPANE

Systematic Name

English

Code System Code Type Description

MERCK INDEX

m9237