1,2-Dichloropropane

Details

Stereochemistry	RACEMIC
Molecular Formula	C3H6Cl2
Molecular Weight	112.986
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(Cl)CCl

InChI

InChIKey=KNKRKFALVUDBJE-UHFFFAOYSA-N

InChI=1S/C3H6Cl2/c1-3(5)2-4/h3H,2H2,1H3

HIDE SMILES / InChI

Molecular Formula	C3H6Cl2
Molecular Weight	112.986
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

PubMed

Title	Date	PubMed
Determination of Hepatotoxicity and Its Underlying Metabolic Basis of 1,2-Dichloropropane in Male Syrian Hamsters and B6C3F1 Mice.	2015-05	25711234
Cholangiocarcinoma among offset colour proof-printing workers exposed to 1,2-dichloropropane and/or dichloromethane.	2013-07	23493378
Determination of phosphine and other fumigants in air samples by thermal desorption and 2D heart-cutting gas chromatography with synchronous SIM/Scan mass spectrometry and flame photometric detection.	2010-12-24	21084090
Occupational reproductive function abnormalities and bladder cancer in Korea.	2010-12	21258590
Inhalation carcinogenicity and toxicity of 1,2-dichloropropane in rats.	2010-11	21070183
Comments on "Degradation of 1,2,3-trichloropropane (TCP): hydrolysis, elimination, and reduction by iron and zinc".	2010-04-15	20192163
Degradation of 1,2,3-trichloropropane (TCP): hydrolysis, elimination, and reduction by iron and zinc.	2010-01-15	20000732
Dehalogenimonas lykanthroporepellens gen. nov., sp. nov., a reductively dehalogenating bacterium isolated from chlorinated solvent-contaminated groundwater.	2009-11	19625421
Stable carbon isotope fractionation of 1,2-dichloropropane during dichloroelimination by Dehalococcoides populations.	2009-09-15	19806720
Characterization of the chronic risk and hazard of hazardous air pollutants in the United States using ambient monitoring data.	2009-05	19479023
Isolation of novel bacteria within the Chloroflexi capable of reductive dechlorination of 1,2,3-trichloropropane.	2009-04	19396942
Distribution of volatile organic compounds in Sicilian groundwaters analysed by head space-solid phase micro extraction coupled with gas chromatography mass spectrometry (SPME/GC/MS).	2008-08	18703213
Affinity-based elimination of aromatic VOCs by highly crystalline multi-walled carbon nanotubes.	2008-02-15	18371779
Occurrence and potential human-health relevance of volatile organic compounds in drinking water from domestic wells in the United States.	2007-11	18007981
Comparative assessment of air pollution-related health risks in Houston.	2007-10	17938725
Quantitative structure-activity relationships for toxicity and genotoxicity of halogenated aliphatic compounds: wing spot test of Drosophila melanogaster.	2007-02	17113125
Bacterial diversity of an acidic Louisiana groundwater contaminated by dense nonaqueous-phase liquid containing chloroethanes and other solvents.	2006-10	16958913
Volatile organic compounds and pulmonary function in the Third National Health and Nutrition Examination Survey, 1988-1994.	2006-08	16882527
The role of syntrophic associations in sustaining anaerobic mineralization of chlorinated organic compounds.	2005-03	15743720
Technological parameters of the ammonolysis of waste 1,2-dichloropropane.	2004-01-30	15177099
Metabolism and mutagenicity of source water contaminants 1,3-dichloropropane and 2,2-dichloropropane.	2004-01	14709629
Adsorption from aqueous solutions of chlorinated organic compounds onto activated carbons.	2003-09-15	12962661
Application of Fenton's reagent to regenerate activated carbon saturated with organochloro compounds.	2003-03	12531711
Acute renal and hepatic failure due to accidental percutaneous absorption of 1,2-dichlorpropane contained in a commercial paint fixative.	2003-01	12480995
Temperature dependence of Henry's law constant in an extended temperature range.	2002-08	12201206
Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition.	2002-04-16	11939779
Microbial structure of an anaerobic bioreactor population that continuously dechlorinates 1,2-dichloropropane.	2002-03-01	19709202
Effects of 1-bromopropane, 2-bromopropane, and 1,2-dichloropropane on the estrous cycle and ovulation in F344 rats.	2002-01-05	11738269
Co-metabolic degradation of chlorinated hydrocarbons by Pseudomonas sp. strain DCA1.	2001-11	11762603
Comparative binding energy analysis of the substrate specificity of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10.	2001-07-31	11467952
Purification, cloning, and sequencing of an enzyme mediating the reductive dechlorination of tetrachloroethylene (PCE) from Clostridium bifermentans DPH-1.	2001-05	11400736
Fate and origin of 1,2-dichloropropane in an unconfined shallow aquifer.	2001-02-01	11351714
Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects.	1991-03-01	1664256
1,2-Dichloropropane (DCP) toxicity is correlated with DCP-induced glutathione (GSH) depletion and is modulated by factors affecting intracellular GSH.	1990	1980407
Oral toxicity of 1,2-dichloropropane: acute, short-term, and long-term studies in rats.	1989-05	2744274
Allergic contact dermatitis from 1,2-dichloropropane.	1989-05	2527719
[Behavior of the excretion of mercapturic acid after administration of 1,2-dichloropropane to the rat].	1988-01-01	3173224
Toxicity in man due to stain removers containing 1,2-dichloropropane.	1985-11	4063220
[Disseminated intravascular coagulation (DIC) caused by 1,2-dichloropropane (commercial trielin). Description of 2 cases].	1985-09-01	4088123

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:39:42 GMT 2025` Edited by `admin` on `Mon Mar 31 19:39:42 GMT 2025`
Record UNII	RRZ023OFWL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1,2-Dichloropropane

Systematic Name

English

DICHLOROPROPANE

Preferred Name

English

NSC-1237

Code

English

1,2-DICHLOROPROPANE [IARC]

Common Name

English

DICHLOROPROPANE [MART.]

Common Name

English

PROPYLENE DICHLORIDE [MI]

Common Name

English

(±)-1,2-DICHLOROPROPANE

Systematic Name

English

1,2-DICHLOROPROPANE [ISO]

Common Name

English

1,2-DICHLOROPROPANE [HSDB]

Common Name

English

Code System Code Type Description

MERCK INDEX

m9237