U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 12:18:55 GMT 2023
Edited
by admin
on Sat Dec 16 12:18:55 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
RO8YK136ZE
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL
Common Name English
REGULATORY PROTEIN SIR2 HOMOLOG 5
Common Name English
SIRT5
Common Name English
SIR2-LIKE PROTEIN 5
Common Name English
Code System Code Type Description
FDA UNII
RO8YK136ZE
Created by admin on Sat Dec 16 12:18:55 GMT 2023 , Edited by admin on Sat Dec 16 12:18:55 GMT 2023
PRIMARY
UNIPROT
Q9NXA8
Created by admin on Sat Dec 16 12:18:55 GMT 2023 , Edited by admin on Sat Dec 16 12:18:55 GMT 2023
PRIMARY
Related Record Type Details
ACTIVATOR -> TARGET
Resveratrol activates deacetylase activity while inhibiting desuccinylase activity.
INHIBITOR -> TARGET
NAD-dependent lysine desuccinylase activity is inhibited by physiological nicotinamide concentrations, while deacetylase activity is not.
INHIBITOR -> TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT CHEMICAL