2,5-DIMETHOXY-N-((2-METHOXYPHENYL)METHYL)BENZENEETHANAMINE

COC1=CC=C(OC)C(CCNCC2=CC=CC=C2OC)=C1

InChIKey=RMLXCDMTGWSEOU-UHFFFAOYSA-N

InChI=1S/C18H23NO3/c1-20-16-8-9-18(22-3)14(12-16)10-11-19-13-15-6-4-5-7-17(15)21-2/h4-9,12,19H,10-11,13H2,1-3H3

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
Serotonin 2c (5-HT2c) receptor 131 Target ID: CHEMBL225 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30261175	Agonist 2752		16.4 nM [Ki]
Serotonin 2a (5-HT2a) receptor 237 Target ID: CHEMBL224 Sources: https://www.ncbi.nlm.nih.gov/pubmed/30261175 \| https://www.ncbi.nlm.nih.gov/pubmed/17000863	Agonist 2752		4.9 nM [Ki]

PubMed

Title	Date	PubMed
Neurochemical pharmacology of psychoactive substituted N-benzylphenethylamines: High potency agonists at 5-HT2A receptors.	2018-12	30261175
Molecular interaction of serotonin 5-HT2A receptor residues Phe339(6.51) and Phe340(6.52) with superpotent N-benzyl phenethylamine agonists.	2006-12	17000863

Substance Class	Chemical Created by `admin` on `Tue Apr 01 16:22:00 GMT 2025` Edited by `admin` on `Tue Apr 01 16:22:00 GMT 2025`
Record UNII	RN5ZVN74Y9
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

25H-NBOME

Preferred Name

English

2,5-DIMETHOXY-N-((2-METHOXYPHENYL)METHYL)BENZENEETHANAMINE

Systematic Name

English

2C-H-NBOME

Common Name

English

BENZENEETHANAMINE, 2,5-DIMETHOXY-N-((2-METHOXYPHENYL)METHYL)-

Systematic Name

English

Classification Tree Code System Code

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