NEUROPEPTIDE Y RECEPTOR TYPE 1

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 16:48:09 GMT 2025` Edited by `admin` on `Tue Apr 01 16:48:09 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	RL60WM77GU
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NPYY1

Preferred Name

English

NEUROPEPTIDE Y RECEPTOR TYPE 1

Common Name

English

NPY1-R

Common Name

English

NPY1R

Common Name

English

Code System Code Type Description

FDA UNII

RL60WM77GU

Created by admin on Tue Apr 01 16:48:09 GMT 2025 , Edited by admin on Tue Apr 01 16:48:09 GMT 2025

PRIMARY

UNIPROT

P25929

Created by admin on Tue Apr 01 16:48:09 GMT 2025 , Edited by admin on Tue Apr 01 16:48:09 GMT 2025

PRIMARY

PHAROS

P25929

Created by admin on Tue Apr 01 16:48:09 GMT 2025 , Edited by admin on Tue Apr 01 16:48:09 GMT 2025

PRIMARY

From	To
1_113	1_198

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_2
N	1_11
N	1_17

Related Record Type Details


					BY7U39XXK0

NEUROPEPTIDE Y

INHIBITOR -> TARGET

Comments:

Binding Assay

Qualification:

IC50

Amount:


					RG9766UGZ8

BIBP-3226

INHIBITOR -> TARGET

Comments:

BIBP3226 is a potent and highly selective Y1 receptor antagonist both in vitro and in vivo.

Qualification:

IC50

Amount:


					5S3JHR3VC1

1-(1-(3-ETHOXYPHENYL)-4-METHYLCYCLOHEXYL)-4-PHENYL-PIPERAZINE, CIS-

INHIBITOR -> TARGET

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_368]	SITE_SPECIFIC	S		DEXFOSFOSERINE	VI4F0K069V
AMINO_ACID_SUBSTITUTION	[1_338]	SITE_SPECIFIC	C		S-PALMITOYL CYSTEINE	08WQ73S7SV

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL