Pegtarviliase

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:17:55 GMT 2025` Edited by `admin` on `Wed Apr 02 10:17:55 GMT 2025`
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	RKK4N4FPA4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Pegtarviliase

Official Name

English

Cystathionine ?-lyase [59-isoleucine,63-leucine,91-methionine,119-aspartic acid,268-arginine,212-[N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene]-L-lysine],311-glycine,339-valine,353-serine] (human isoform 1), 1,N6-amide with ?-(ca

Preferred Name

English

pegtarviliase [INN]

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C190484

Created by admin on Wed Apr 02 10:17:55 GMT 2025 , Edited by admin on Wed Apr 02 10:17:55 GMT 2025

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SMS_ID

300000022653

Created by admin on Wed Apr 02 10:17:55 GMT 2025 , Edited by admin on Wed Apr 02 10:17:55 GMT 2025

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FDA UNII

RKK4N4FPA4

Created by admin on Wed Apr 02 10:17:55 GMT 2025 , Edited by admin on Wed Apr 02 10:17:55 GMT 2025

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INN

12359

Created by admin on Wed Apr 02 10:17:55 GMT 2025 , Edited by admin on Wed Apr 02 10:17:55 GMT 2025

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CAS

2649372-23-4

Created by admin on Wed Apr 02 10:17:55 GMT 2025 , Edited by admin on Wed Apr 02 10:17:55 GMT 2025

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Related Record Type Details


					RKK4N4FPA4

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
PEGYLATION	[1_1] [2_1] [3_1] [4_1]	N-TERMINUS			MPEG 5000 acetyl methionine	CNY3KQ3UW3
AMINO_ACID_SUBSTITUTION	[1_212] [2_212] [3_212] [4_212]	SITE_SPECIFIC			N6-(PYRIDOXAL PHOSPHATE)LYSINE	QM00M3504A
PEGYLATION	[1_4] [1_73] [1_141] [1_288] [1_330] [2_4] [2_73] [2_141] [2_288] [2_330] [3_4] [3_73] [3_141] [3_288] [3_330] [4_4] [4_73] [4_141] [4_288] [4_330]	SITE_SPECIFIC	K	Amount:	MPEG 5000 acetyl lysine	RX829QLJ56

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL