U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C28H37N5O7
Molecular Weight 555.6227
Optical Activity UNSPECIFIED
Defined Stereocenters 3 / 3
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEUCINE ENKEPHALIN

SMILES

CC(C)C[C@H](NC(=O)[C@H](CC1=CC=CC=C1)NC(=O)CNC(=O)CNC(=O)[C@@H](N)CC2=CC=C(O)C=C2)C(O)=O

InChI

InChIKey=URLZCHNOLZSCCA-VABKMULXSA-N
InChI=1S/C28H37N5O7/c1-17(2)12-23(28(39)40)33-27(38)22(14-18-6-4-3-5-7-18)32-25(36)16-30-24(35)15-31-26(37)21(29)13-19-8-10-20(34)11-9-19/h3-11,17,21-23,34H,12-16,29H2,1-2H3,(H,30,35)(H,31,37)(H,32,36)(H,33,38)(H,39,40)/t21-,22-,23-/m0/s1

HIDE SMILES / InChI

Molecular Formula C28H37N5O7
Molecular Weight 555.6227
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 3 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Anticonvulsants specific for petit mal antagonize epileptogenic effect of leucine enkephalin.
1980 Nov 28
Seizures induced by carbachol, morphine, and leucine-enkephalin: a comparison.
1983 Apr
Inhibition of vagal transmission by cardiac sympathetic nerve stimulation in the dog: possible involvement of opioid receptor.
1989 Sep
Cloning and pharmacological characterization of a rat kappa opioid receptor.
1993 Nov 1
Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.
1994 Feb
Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications.
1998 Mar
Identification of dipeptidyl peptidase III in human neutrophils.
2000 Jul 5
Translating DNA into synthetic molecules.
2004 Jul
A selective fluorescence reaction for peptides and chromatographic analysis.
2008 Mar
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:52:40 GMT 2023
Edited
by admin
on Fri Dec 15 15:52:40 GMT 2023
Record UNII
RI01R707R6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEUCINE ENKEPHALIN
Common Name English
TYR-GLY-GLY-PHE-LEU
Common Name English
ICI-114740
Code English
SM-PEPTIDE-1
Brand Name English
PENTAPEPTIDE-5
INCI  
INCI  
Official Name English
L-LEUCINE, L-TYROSYLGLYCYLGLYCYL-L-PHENYLALANYL-
Systematic Name English
LEU-ENKEPHALIN
Common Name English
SH-PENTAPEPTIDE-5 [INCI]
Common Name English
PENTAPEPTIDE-5 [INCI]
Common Name English
SH-PENTAPEPTIDE-5
INCI  
INCI  
Official Name English
NSC-350588
Code English
Code System Code Type Description
PUBCHEM
461776
Created by admin on Fri Dec 15 15:52:40 GMT 2023 , Edited by admin on Fri Dec 15 15:52:40 GMT 2023
PRIMARY
CAS
58822-25-6
Created by admin on Fri Dec 15 15:52:40 GMT 2023 , Edited by admin on Fri Dec 15 15:52:40 GMT 2023
PRIMARY
NSC
350588
Created by admin on Fri Dec 15 15:52:40 GMT 2023 , Edited by admin on Fri Dec 15 15:52:40 GMT 2023
PRIMARY
WIKIPEDIA
LEU-ENKEPHALIN
Created by admin on Fri Dec 15 15:52:40 GMT 2023 , Edited by admin on Fri Dec 15 15:52:40 GMT 2023
PRIMARY
ECHA (EC/EINECS)
261-457-1
Created by admin on Fri Dec 15 15:52:40 GMT 2023 , Edited by admin on Fri Dec 15 15:52:40 GMT 2023
PRIMARY
CHEBI
89656
Created by admin on Fri Dec 15 15:52:40 GMT 2023 , Edited by admin on Fri Dec 15 15:52:40 GMT 2023
PRIMARY
FDA UNII
RI01R707R6
Created by admin on Fri Dec 15 15:52:40 GMT 2023 , Edited by admin on Fri Dec 15 15:52:40 GMT 2023
PRIMARY
EPA CompTox
DTXSID00905127
Created by admin on Fri Dec 15 15:52:40 GMT 2023 , Edited by admin on Fri Dec 15 15:52:40 GMT 2023
PRIMARY