Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C17H17F2N3O3.ClH |
| Molecular Weight | 385.793 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.NC1CCN(C1)C2=C(F)C3=C(C=C2F)C(=O)C(=CN3C4CC4)C(O)=O
InChI
InChIKey=UVQHUSOZEFWVIY-UHFFFAOYSA-N
InChI=1S/C17H17F2N3O3.ClH/c18-12-5-10-14(13(19)15(12)21-4-3-8(20)6-21)22(9-1-2-9)7-11(16(10)23)17(24)25;/h5,7-9H,1-4,6,20H2,(H,24,25);1H
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C17H17F2N3O3 |
| Molecular Weight | 349.332 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| In vitro activities of free and liposomal drugs against Mycobacterium avium-M. intracellulare complex and M. tuberculosis. | 1993 Dec |
|
| Anti-Mycobacterium avium activity of quinolones: in vitro activities. | 1993 Sep |
|
| In vitro anti-Mycobacterium avium activities of quinolones: predicted active structures and mechanistic considerations. | 1994 Aug |
|
| Activity of quinolones against mycobacteria. | 1995 |
|
| Comparison of the activity of fluoroquinolones against Mycobacterium avium in cell-free systems and a human monocyte in-vitro infection model. | 1996 Mar |
|
| Structure-activity relationships of quinolone agents against mycobacteria: effect of structural modifications at the 8 position. | 1996 Oct |
|
| Activity of new quinolones against intracellular Mycobacterium avium in human monocytes. | 1997 Dec |
|
| The 2-pyridone antibacterial agents: bacterial topoisomerase inhibitors. | 2000 Jul |
|
| Prediction of quinolone activity against Mycobacterium avium by molecular topology and virtual computational screening. | 2000 Oct |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 15:03:37 GMT 2023
by
admin
on
Fri Dec 15 15:03:37 GMT 2023
|
| Record UNII |
REU1QTB262
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
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REU1QTB262
Created by
admin on Fri Dec 15 15:03:37 GMT 2023 , Edited by admin on Fri Dec 15 15:03:37 GMT 2023
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13590048
Created by
admin on Fri Dec 15 15:03:37 GMT 2023 , Edited by admin on Fri Dec 15 15:03:37 GMT 2023
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106797-94-8
Created by
admin on Fri Dec 15 15:03:37 GMT 2023 , Edited by admin on Fri Dec 15 15:03:37 GMT 2023
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PRIMARY |
| Related Record | Type | Details | ||
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PARENT -> SALT/SOLVATE |
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ACTIVE MOIETY |