ROLZIRACETAM

Details

Stereochemistry	ACHIRAL
Molecular Formula	C7H9NO2
Molecular Weight	139.1519
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O=C1CCC2CCC(=O)N12

InChI

InChIKey=IEZDOKQWPWZVQF-UHFFFAOYSA-N

InChI=1S/C7H9NO2/c9-6-3-1-5-2-4-7(10)8(5)6/h5H,1-4H2

HIDE SMILES / InChI

Molecular Formula	C7H9NO2
Molecular Weight	139.1519
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/3691579 | https://www.ncbi.nlm.nih.gov/pubmed/3820221 | https://www.acimmune.com/content/resources/froestl_2012_part1.pdf

Rolziracetam (CI-911) is a nootropic drug. In several animal species (monkey, dogs, and rats) it was found to be rapidly eliminated from the body with a half-life of less than 25 min. Rolziracetam improved performance on a delayed-response task in aged rhesus monkeys. The drug was ineffective in a scopolamine-induced amnesia mouse model, in contrast to other nootropic drugs. Development of this piracetam-type cognitive enhancer was terminated.

Originator

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:48:23 GMT 2023` Edited by `admin` on `Sat Dec 16 16:48:23 GMT 2023`
Record UNII	RES9I0LGG5
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ROLZIRACETAM

Official Name

English

DIHYDRO-1H-PYRROLIZINE-3,5(2H,6H)-DIONE

Systematic Name

English

NSC-122751

Code

English

rolziracetam [INN]

Common Name

English

CI-911

Code

English

Classification Tree Code System Code

NCI_THESAURUS

C1509