PRALUZATAMAB RAVTANSINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 17:40:35 GMT 2023` Edited by `admin` on `Sat Dec 16 17:40:35 GMT 2023`
Protein Type	PROBODY
Protein Sub Type	TOXIN CONJUGATE
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	RD2I59M9FC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PRALUZATAMAB RAVTANSINE

Official Name

English

PRALUZATAMAB RAVTANSINE [USAN]

Common Name

English

praluzatamab ravtansine [INN]

Common Name

English

Praluzatamab ravtansine [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS CD166 ANTIGEN (ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE)); HUMANIZED MONOCLONAL ANTIBODY; .GAMMA.1 HEAVY CHAIN HUMANIZED (1-450) (VH (HOMO SAPIENS IGHV2-5*01 (89%) (IGHD)-IGHJ4*01 (93%)) (10.7.13) (1-121)-HOM

Common Name

English

CX-2009

Code

English

ANTI-CD166 PROBODY-DRUG CONJUGATE CX-2009

Common Name

English

ANTI-CD166-DM4 CX-2009

Common Name

English

Code System Code Type Description

CAS

2145115-85-9

Created by admin on Sat Dec 16 17:40:36 GMT 2023 , Edited by admin on Sat Dec 16 17:40:36 GMT 2023

PRIMARY

NCI_THESAURUS

C134697

Created by admin on Sat Dec 16 17:40:36 GMT 2023 , Edited by admin on Sat Dec 16 17:40:36 GMT 2023

PRIMARY

FDA UNII

RD2I59M9FC

Created by admin on Sat Dec 16 17:40:36 GMT 2023 , Edited by admin on Sat Dec 16 17:40:36 GMT 2023

PRIMARY

INN

10939

Created by admin on Sat Dec 16 17:40:36 GMT 2023 , Edited by admin on Sat Dec 16 17:40:36 GMT 2023

PRIMARY

USAN

HI-169

Created by admin on Sat Dec 16 17:40:36 GMT 2023 , Edited by admin on Sat Dec 16 17:40:36 GMT 2023

PRIMARY

From	To
1_22	1_97
1_148	1_204
1_224	3_270
1_230	2_230
1_233	2_233
1_265	1_325
1_371	1_429
2_22	2_97
2_148	2_204
2_224	4_270
2_265	2_325
2_371	2_429
3_9	3_20
3_74	3_144
4_9	4_20
4_74	4_144
3_190	3_250
4_190	4_250

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					6MDF4WB915

DM4-SPDB-L-LYSINE

CONJUGATE COMPONENT->CONJUGATE


					WB7H35ST8W

MATRIX METALLOPROTEINASE-14

METABOLIC ENZYME -> SUBSTRATE

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL