U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C2H3ClO2
Molecular Weight 94.497
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Methyl chloroformate

SMILES

COC(Cl)=O

InChI

InChIKey=XMJHPCRAQCTCFT-UHFFFAOYSA-N
InChI=1S/C2H3ClO2/c1-5-2(3)4/h1H3

HIDE SMILES / InChI

Molecular Formula C2H3ClO2
Molecular Weight 94.497
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Yeast biological networks unfold the interplay of antioxidants, genome and phenotype, and reveal a novel regulator of the oxidative stress response.
2010-10-25
Determination of octylphenol and nonylphenol in aqueous sample using simultaneous derivatization and dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry.
2010-10-22
Analytical platform for metabolome analysis of microbial cells using methyl chloroformate derivatization followed by gas chromatography-mass spectrometry.
2010-09
Microscale analysis of amino acids using gas chromatography-mass spectrometry after methyl chloroformate derivatization.
2010-08-15
Characterization of the branched-chain amino acid aminotransferase enzyme family in tomato.
2010-07
Analysis of the nucleophilic solvation effects in isopropyl chlorothioformate solvolysis.
2010-06-29
Use of empirical correlations to determine solvent effects in the solvolysis of S-methyl chlorothioformate.
2010-05-25
Comparison of derivatization and chromatographic methods for GC-MS analysis of amino acid enantiomers in physiological samples.
2010-05-01
Fused bicyclic piperidines and dihydropyridines by dearomatising cyclisation of the enolates of nicotinyl-substituted esters and ketones.
2010-03-02
Enantiomeric resolution of biomarkers in space analysis: Chemical derivatization and signal processing for gas chromatography-mass spectrometry analysis of chiral amino acids.
2010-02-12
Corrrelation of the specific rates of solvolysis of ethyl fluoroformate using the extended Grunwald-Winstein equation.
2009-03
Grunwald-Winstein analysis: isopropyl chloroformate solvolysis revisited.
2009-03
Selective inhibition of carotenoid cleavage dioxygenases: phenotypic effects on shoot branching.
2009-02-20
Extended Grunwald-Winstein analysis - LFER used to gauge solvent effects in p-nitrophenyl chloroformate solvolysis.
2008-11
Synthesis of azoxabicyclo[3.3.1]nonanones based on diastereoselective reactions of 1,1-bis(trimethylsilyloxy)ketene acetals with isoquinolines and quinolines.
2008-08-07
New nordihydroguaiaretic acid derivatives as anti-HIV agents.
2008-03-15
Identification of biomarkers for genotyping Aspergilli using non-linear methods for clustering and classification.
2008-01-28
Large-scale synthesis of a persistent trityl radical for use in biomedical EPR applications and imaging.
2007-12-15
The first solid enols of anhydrides. Structure, properties, and enol/anhydride equilibria(1).
2007-11-23
Gas chromatography-mass spectrometry analysis of amino acid enantiomers as methyl chloroformate derivatives: application to space analysis.
2007-05-25
The oriented development of antituberculotics (Part II): halogenated 3-(4-alkylphenyl)-1,3-benzoxazine-2,4-(3H)-diones.
2007-05
Characterization of the methoxy carbonyl radical formed via photolysis of methyl chloroformate at 193.3 nm.
2007-03-15
Enantiomeric analysis of amino acids by using comprehensive two-dimensional gas chromatography.
2007-03
Quantitative profiling of folate and one-carbon metabolism in large-scale epidemiological studies by mass spectrometry.
2007
An evaluation of GC-MS and HPLC-FD methods for analysis of protein binders in paintings.
2006-11
Study of the microbiodegradation of terpenoid resin-based varnishes from easel painting using pyrolysis-gas chromatography-mass spectrometry and gas chromatography-mass spectrometry.
2006-08
Analysis of phenolic acids as chloroformate derivatives using solid phase microextraction-gas chromatography.
2006-07-28
Do alpha-acyloxy and alpha-alkoxycarbonyloxy radicals fragment to form acyl and alkoxycarbonyl radicals?
2006-05-25
Unimolecular dissociation of the CH3OCO radical: an intermediate in the CH3O + CO reaction.
2006-02-02
Study of Burseraceae resins used in binding media and varnishes from artworks by gas chromatography-mass spectrometry and pyrolysis-gas chromatography-mass spectrometry.
2005-11-04
Automated assay for the determination of methylmalonic acid, total homocysteine, and related amino acids in human serum or plasma by means of methylchloroformate derivatization and gas chromatography-mass spectrometry.
2005-11
Mechanisms of solvolyses of acid chlorides and chloroformates. Chloroacetyl and phenylacetyl chloride as similarity models.
2005-10-28
A comparative study of several HPLC methods for determining free amino acid profiles in honey.
2005-06
Comparison of extraction methods for quantitation of methionine and selenomethionine in yeast by species specific isotope dilution gas chromatography-mass spectrometry.
2004-11-05
Determination of methionine and selenomethionine in yeast by species-specific isotope dilution GC/MS.
2004-09-01
An investigation of the N-demethylation of 3-deoxymorphine and the affinity of the alkylation products to mu, delta, and kappa receptors.
2004-05-15
Effect of a new beta-sitosterol analogue on plasma lipid concentrations in rats.
2004-05
Solid-phase synthesis of 5-isoxazol-4-yl-[1,2,4]oxadiazoles.
2004-03-05
Two trace analytical methods for determination of hydroxylated PCBs and other halogenated phenolic compounds in eggs from Norwegian birds of prey.
2004-01-15
Stereospecific Pd(0)-catalyzed arylation of an allylic hydroxy phosphonate derivative: formal synthesis of (S)-(+)-ar-turmerone.
2003-11-28
Simultaneous analysis of amino and nonamino organic acids as methyl chloroformate derivatives using gas chromatography-mass spectrometry.
2003-11-01
Comparison of different chloroformates for the derivatisation of seleno amino acids for gas chromatographic analysis.
2003-10-10
New process for the preparation of methyl carbonates.
2003-05-01
Complex-induced proximity effects. Temperature-dependent regiochemical diversity in lithiation-electrophilic substitution reactions of N-BOC-2-azabicyclo[2.1.1]hexane. 2,4- and 3,5-methanoprolines.
2002-09-05
Analysis of carnitine biosynthesis metabolites in urine by HPLC-electrospray tandem mass spectrometry.
2002-06
One pot synthesis of nitrogen-containing polycyclic delta-lactones by double nucleophilic addition of bis(trimethylsilyl)ketene acetals to pyridines.
2002-05-07
[Intramolecular alkylation of aromatic compounds. 35. Di- and tetrahydropyridinemethylindolines as potential precursors of ergolines] .
2001-01
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:51:36 GMT 2025
Edited
by admin
on Mon Mar 31 18:51:36 GMT 2025
Record UNII
RC6VA8OB2N
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Methyl chloroformate
HSDB  
Systematic Name English
Methyl chlorocarbonate
MI  
Preferred Name English
CARBONOCHLORIDIC ACID METHYL ESTER
Systematic Name English
METHYL CHLOROFORMATE [HSDB]
Common Name English
METHYL CHLOROCARBONATE [MI]
Common Name English
Code System Code Type Description
HSDB
1116
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY
ECHA (EC/EINECS)
201-187-3
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY
PUBCHEM
6586
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY
FDA UNII
RC6VA8OB2N
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY
WIKIPEDIA
METHYL CHLOROFORMATE
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY
EPA CompTox
DTXSID0024185
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY
CAS
79-22-1
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY
MERCK INDEX
m7384
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY Merck Index
MESH
C014667
Created by admin on Mon Mar 31 18:51:36 GMT 2025 , Edited by admin on Mon Mar 31 18:51:36 GMT 2025
PRIMARY