PHENYL BUTYRATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H12O2
Molecular Weight	164.2011
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCC(=O)OC1=CC=CC=C1

InChI

InChIKey=IGVPBCZDHMIOJH-UHFFFAOYSA-N

InChI=1S/C10H12O2/c1-2-6-10(11)12-9-7-4-3-5-8-9/h3-5,7-8H,2,6H2,1H3

HIDE SMILES / InChI

Molecular Formula	C10H12O2
Molecular Weight	164.2011
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Pharmacological approaches to correcting the ion transport defect in cystic fibrosis.	2003	14719993
Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment.	2005	16339672
Fetal haemoglobin augmentation in E/beta(0) thalassaemia: clinical and haematological outcome.	2005 Nov	16225658
Effects of histone deacetylase inhibitors, sodium phenyl butyrate and vitamin B3, in combination with retinoic acid on granulocytic differentiation of human promyelocytic leukemia HL-60 cells.	2006 Dec	17341628
[Phenol butyrate inhibits cell cycle of leukemia cell lines through up-regulation of p21WAF1/CIP1 gene].	2006 May	16875574
Sodium phenyl butyrate downregulates endothelin-1 expression in cultured human endothelial cells: relevance to sickle-cell disease.	2007 May	17373676
Influence of aromatic and aliphatic moieties on thrombin inhibitors potency.	2008	19238188
Non-protein coding RNA biomarkers and differential expression in cancers: a review.	2008 Jul 16	18631387
Response of retinoic acid-resistant KG1 cells to combination of retinoic acid with diverse histone deacetylase inhibitors.	2009 Aug	19723072
[Ornithine transcarbamylase deficiency in adolescence and adulthood: first manifestation with life-threatening decompensation].	2009 Jun	19468698
Detection of metabolite changes in C6 glioma cells cultured with antimitotic oleyl glycoside by 1H MAS NMR.	2009 Mar 12	19199478
Grp78 heterozygosity regulates chaperone balance in exocrine pancreas with differential response to cerulein-induced acute pancreatitis.	2010 Dec	20971738
Downregulation of homologous recombination DNA repair genes by HDAC inhibition in prostate cancer is mediated through the E2F1 transcription factor.	2010 Jun 18	20585447
Homeostatic imbalance of purine catabolism in first-episode neuroleptic-naïve patients with schizophrenia.	2010 Mar 3	20209081
Epigenetics of royalty.	2010 Nov 2	21072243
The honey bee epigenomes: differential methylation of brain DNA in queens and workers.	2010 Nov 2	21072239
Evaluation of histone deacetylases as drug targets in Huntington's disease models. Study of HDACs in brain tissues from R6/2 and CAG140 knock-in HD mouse models and human patients and in a neuronal HD cell model.	2010 Sep 2	20877454

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:54:13 GMT 2023` Edited by `admin` on `Fri Dec 15 17:54:13 GMT 2023`
Record UNII	R9K49A127H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PHENYL BUTYRATE

Systematic Name

English

BUTANOIC ACID, PHENYL ESTER

Common Name

English

PHENYL BUTANOATE

Systematic Name

English

BUTYRIC ACID, PHENYL ESTER

Common Name

English

FEMA NO. 4621

Code

English

Classification Tree Code System Code

JECFA EVALUATION

PHENYL BUTYRATE