Details
| Stereochemistry | UNKNOWN |
| Molecular Formula | C19H25NO |
| Molecular Weight | 283.4079 |
| Optical Activity | ( + ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)NCC(O)CC(C1=CC=CC=C1)C2=CC=CC=C2
InChI
InChIKey=DAIZVBCVNQSHLI-UHFFFAOYSA-N
InChI=1S/C19H25NO/c1-15(2)20-14-18(21)13-19(16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-12,15,18-21H,13-14H2,1-2H3
| Molecular Formula | C19H25NO |
| Molecular Weight | 283.4079 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Drobuline is a potent cardiac depressant (anti-arrhythmic) agent, which has been found to be effective against ventricular arrhythmias in dogs. This compound is a racemic mixture having a single center of optical activity. The two isomers of drobuline were found to be equally potent in converting cardiac arrhythmias in dogs after intravenous administration. The major route of biotransformation of drobuline in the dog was shown to be conjugation with glucuronic acid.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/692260
Curator's Comment: Dogs data
Single dose - 10 mg/kg
Route of Administration:
Oral
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:39:26 GMT 2025
by
admin
on
Mon Mar 31 22:39:26 GMT 2025
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| Record UNII |
R97AZJ8FZL
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| Record Status |
Validated (UNII)
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| Record Version |
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R97AZJ8FZL
Created by
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68341-48-0
Created by
admin on Mon Mar 31 22:39:26 GMT 2025 , Edited by admin on Mon Mar 31 22:39:26 GMT 2025
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