Details
Stereochemistry | UNKNOWN |
Molecular Formula | C19H25NO |
Molecular Weight | 283.4079 |
Optical Activity | ( + ) |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)NCC(O)CC(C1=CC=CC=C1)C2=CC=CC=C2
InChI
InChIKey=DAIZVBCVNQSHLI-UHFFFAOYSA-N
InChI=1S/C19H25NO/c1-15(2)20-14-18(21)13-19(16-9-5-3-6-10-16)17-11-7-4-8-12-17/h3-12,15,18-21H,13-14H2,1-2H3
Molecular Formula | C19H25NO |
Molecular Weight | 283.4079 |
Charge | 0 |
Count |
|
Stereochemistry | RACEMIC |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 1 |
E/Z Centers | 0 |
Optical Activity | ( + / - ) |
Drobuline is a potent cardiac depressant (anti-arrhythmic) agent, which has been found to be effective against ventricular arrhythmias in dogs. This compound is a racemic mixture having a single center of optical activity. The two isomers of drobuline were found to be equally potent in converting cardiac arrhythmias in dogs after intravenous administration. The major route of biotransformation of drobuline in the dog was shown to be conjugation with glucuronic acid.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/692260
Curator's Comment: Dogs data
Single dose - 10 mg/kg
Route of Administration:
Oral
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 09:24:29 GMT 2023
by
admin
on
Sat Dec 16 09:24:29 GMT 2023
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Record UNII |
R97AZJ8FZL
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Record Status |
Validated (UNII)
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Record Version |
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68341-48-0
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60890
Created by
admin on Sat Dec 16 09:24:29 GMT 2023 , Edited by admin on Sat Dec 16 09:24:29 GMT 2023
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