U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Fri Jun 25 21:30:29 UTC 2021
Edited
by admin
on Fri Jun 25 21:30:29 UTC 2021
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
R96Z451BMC
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AXATILIMAB
INN   USAN  
Official Name English
IMMUNOGLOBULIN G4, ANTI-(HUMAN COLONY-STIMULATING FACTOR 1 RECEPTOR) (HUMAN-RATTUS NORVEGICUS MONOCLONAL SNDX-6352 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN-RATTUS NORVEGICUS MONOCLONAL SNDX-6352 .KAPPA.-CHAIN, DIMER
Common Name English
SNDX-6352
Code English
AXATILIMAB [INN]
Common Name English
ANTI-CSF1R MONOCLONAL ANTIBODY SNDX-6352
Common Name English
AXATILIMAB [USAN]
Common Name English
AXATILIMAB [WHO-DD]
Common Name English
UCB-6352
Code English
UCB6352
Code English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS MACROPHAGE COLONY-STIMULATING FACTOR 1 RECEPTOR (PROTO-ONCOGENE C-FMS; CSF-1-R; CD115_ANTIGEN)); HUMANIZED MONOCLONAL ANTIBODY; .GAMMA.4 HEAVY CHAIN HUMANIZED (1-453) (HOMO SAPIENS VH (IGHV2-70*11 (90%) (IGHD)-
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 732320
Created by admin on Fri Jun 25 21:30:29 UTC 2021 , Edited by admin on Fri Jun 25 21:30:29 UTC 2021
FDA ORPHAN DRUG 807821
Created by admin on Fri Jun 25 21:30:29 UTC 2021 , Edited by admin on Fri Jun 25 21:30:29 UTC 2021
Code System Code Type Description
NCI_THESAURUS
C155813
Created by admin on Fri Jun 25 21:30:29 UTC 2021 , Edited by admin on Fri Jun 25 21:30:29 UTC 2021
PRIMARY
INN
10953
Created by admin on Fri Jun 25 21:30:29 UTC 2021 , Edited by admin on Fri Jun 25 21:30:29 UTC 2021
PRIMARY
FDA UNII
R96Z451BMC
Created by admin on Fri Jun 25 21:30:29 UTC 2021 , Edited by admin on Fri Jun 25 21:30:29 UTC 2021
PRIMARY
From To
1_22 1_97
1_140 3_214
1_153 1_209
1_232 2_232
1_235 2_235
1_267 1_327
1_373 1_431
2_22 2_97
2_140 4_214
2_153 2_209
2_267 2_327
2_373 2_431
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_303
N 2_303
Related Record Type Details
TARGET -> INHIBITOR
Prevents the binding of both colony stimulating factor 1 (CSF-1) and interleukin 34 (IL-34) to CSF-1R
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL