LESABELIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 10:20:34 GMT 2025` Edited by `admin` on `Wed Apr 02 10:20:34 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	R8ZW84Q6SU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

IMMUNOGLOBULIN G1, ANTI-(HUMAN PROGRAMMED DEATH-LIGAND 1) (HUMAN MONOCLONAL LDP .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL LDP .KAPPA.-CHAIN, DIMER

Preferred Name

English

LESABELIMAB

Official Name

English

lesabelimab [INN]

Common Name

English

Code System Code Type Description

SMS_ID

300000049565

Created by admin on Wed Apr 02 10:20:34 GMT 2025 , Edited by admin on Wed Apr 02 10:20:34 GMT 2025

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FDA UNII

R8ZW84Q6SU

Created by admin on Wed Apr 02 10:20:34 GMT 2025 , Edited by admin on Wed Apr 02 10:20:34 GMT 2025

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NCI_THESAURUS

C203035

Created by admin on Wed Apr 02 10:20:34 GMT 2025 , Edited by admin on Wed Apr 02 10:20:34 GMT 2025

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INN

11914

Created by admin on Wed Apr 02 10:20:34 GMT 2025 , Edited by admin on Wed Apr 02 10:20:34 GMT 2025

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CAS

2475402-56-1

Created by admin on Wed Apr 02 10:20:34 GMT 2025 , Edited by admin on Wed Apr 02 10:20:34 GMT 2025

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From	To
1_22	1_97
2_22	2_97
2_145	2_201
2_221	4_216
2_262	2_322
1_145	1_201
2_368	2_426
3_23	3_88
3_136	3_196
4_23	4_88
4_136	4_196
1_221	3_216
1_227	2_227
1_230	2_230
1_262	1_322
1_368	1_426

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_448] [2_448]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL