4,4'-BIPHENYLDIOL

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H10O2
Molecular Weight	186.2066
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=CC=C(C=C1)C2=CC=C(O)C=C2

InChI

InChIKey=VCCBEIPGXKNHFW-UHFFFAOYSA-N

InChI=1S/C12H10O2/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10/h1-8,13-14H

HIDE SMILES / InChI

Molecular Formula	C12H10O2
Molecular Weight	186.2066
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Bisphenol A binds to Ras proteins and competes with guanine nucleotide exchange: implications for GTPase-selective antagonists.	2013-12-12	24266771
Preparation of dummy template imprinted polymers at surface of silica microparticles for the selective extraction of trace bisphenol A from water samples.	2010-07-15	20347520
Time-dependent integrity during storage of natural surface water samples for the trace analysis of pharmaceutical products, feminizing hormones and pesticides.	2010-04-19	20403158
Antioxidant and cyclooxygenase-2-inhibiting activity of 4,4'-biphenol, 2,2'-biphenol and phenol.	2009-06	19528508
Synthesis and drug release properties of poly(ethylene oxide) segmented polysulfone copolymers.	2008-05-08	18353482
Directed synthesis of hierarchical nanostructured TiO2 catalysts and their morphology-dependent photocatalysis for phenol degradation.	2008-04-01	18504963
Effect of substituents in aromatic amines on the activation energy of epoxy-amine reaction.	2007-06-28	17530886
Experimental and theoretical study of the CD spectra and conformational properties of axially chiral 2,2'-, 3,3'-, and 4,4'-biphenol ethers.	2007-05-24	17472357
Self-assembly and host-guest chemistry of a 3.5-nm coordination nanotube.	2007-04-02	17441183
Ultrafast electron-transfer and solvent adiabaticity effects in viologen charge-transfer complexes.	2006-11-16	17091938
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.	2006-11	16497524
Lignan compounds and 4,4'-dihydroxybiphenyl protect C2C12 cells against damage from oxidative stress.	2006-05-26	16616009
Lumped kinetics and acute toxicity of intermediates in the ozonation of phenol in saline media.	2006-02-06	16144743
Inhibition of melanogenic activity by 4,4'-dihydroxybiphenyl in melanoma cells.	2006-01	16394501
Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth.	2006	16427523
Hydrogen bonding patterns in the cocrystals of 5-nitrouracil with several donor and acceptor molecules.	2005-12-09	16542030
Stimulation of topoisomerase II-mediated DNA cleavage by benzene metabolites.	2005-05-30	15935817
Effects of benzene metabolites on DNA cleavage mediated by human topoisomerase II alpha: 1,4-hydroquinone is a topoisomerase II poison.	2005-04	15833037
Solvent adiabaticity effects on ultrafast electron transfer in viologen charge transfer complexes.	2005-03-10	16833508
4,4'-Dihydroxybiphenyl as a new potent tyrosinase inhibitor.	2005-02	15684492
Probing the peripheral anionic site of acetylcholinesterase with quantitative structure activity relationships for inhibition by biphenyl-4-acyoxylate-4'-N-Butylcarbamates.	2005	16173062
Photocatalytic one-electron oxidation of biphenyl derivatives strongly coupled with the TiO2 surface.	2004-03-30	15835148
Comparative study of the uterotrophic potency of 14 chemicals in a uterotrophic assay and their receptor-binding affinity.	2004-01-15	14643963
Effects of the environmental oestrogens bisphenol A, tetrachlorobisphenol A, tetrabromobisphenol A, 4-hydroxybiphenyl and 4,4'-dihydroxybiphenyl on oestrogen receptor binding, cell proliferation and regulation of oestrogen sensitive proteins in the human breast cancer cell line MCF-7.	2003-04	12753421
Computational studies on pseudorotaxanes by molecular dynamics and free energy perturbation simulations.	2003-02-21	12585899
Phenylphenols, biphenols, bisphenol-A and 4-tert-octylphenol exhibit alpha and beta estrogen activities and antiandrogen activity in reporter cell lines.	2002-07-31	12161000
Benzene metabolites antagonize etoposide-stabilized cleavable complexes of DNA topoisomerase IIalpha.	2001-08-01	11468185
Inhibition of environmental estrogen-induced proliferation of human breast carcinoma MCF-7 cells by flavonoids.	2001-05	11513082

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:30:06 GMT 2025` Edited by `admin` on `Mon Mar 31 19:30:06 GMT 2025`
Record UNII	R8994A0904
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

4,4'-BIPHENYLDIOL

Systematic Name

English

DIHYDROXYBIPHENYL

Preferred Name

English

4,4'-BIPHENOL

Systematic Name

English

GM-W07

Brand Name

English

GM-W06

Brand Name

English

4,4'-DIHYDROXY-1,1'-BIPHENYL

Systematic Name

English

4,4'-DIHYDROXYBIPHENYL

Systematic Name

English

DOD

Brand Name

English

BIPHENYL-4,4'-DIOL

Systematic Name

English

4,4'-BISPHENOL

Common Name

English

4,4'-DIHYDROXYDIPHENYL

Common Name

English

NSC-8711

Code

English

P,P'-BIPHENOL

Common Name

English

(1,1'-BIPHENYL)-4,4'-DIOL

Systematic Name

English

Code System Code Type Description

EVMPD

SUB169669