GLYCERYL 1,2-DIPALMITATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C35H68O5
Molecular Weight	568.9114
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCCCCCCCC

InChI

InChIKey=JEJLGIQLPYYGEE-UHFFFAOYSA-N

InChI=1S/C35H68O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-34(37)39-32-33(31-36)40-35(38)30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h33,36H,3-32H2,1-2H3

HIDE SMILES / InChI

Molecular Formula	C35H68O5
Molecular Weight	568.9114
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/22707832

There is no much information in the literature related to the biological and pharmacological application of GLYCERYL 1,2-DIPALMITATE. It is known, that this compound is a component of the seeds of Carica papaya L. (Caricaceae), which showed antifungal activity against Aspergillus flavus, Candida albicans, and Penicillium citrinium.

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2578

PubMed

Title	Date	PubMed
Chemical constituents of Typhonium giganteum Engl.	2001	11783581
Phosphatidylcholine de novo synthesis and modification are carried out sequentially in HL60 cells: evidence from mass isotopomer distribution analysis.	2004 Jun 29	15209508
Analysis of 1,2(2,3)- and 1,3-positional isomers of diacylglycerols from vegetable oils by reversed-phase high-performance liquid chromatography.	2004 Mar	15023251
Micro-scale flow cytometry-based and biochemical analysis of lipid signaling in primary B cell subpopulations.	2007 Dec 24	18385809
Modifying dipalmitoylphosphatidylcholine monolayers by n-hexadecanol and dipalmitoylglycerol.	2007 Feb	17187768
Atomic force microscope visualization of lipid bilayer degradation due to action of phospholipase A2 and Humicola lanuginosa lipase.	2007 Jan	17084807
Lateral intermolecular forces between biomembrane lipids in two dimensions: 1,2-dipalmitin at the heptane/water interface compared with phospholipids.	2007 Jan 11	17201430
Lipids of human meibum: mass-spectrometric analysis and structural elucidation.	2007 Oct	17626978
Well-defined and potent liposomal hepatitis B vaccines adjuvanted with lipophilic MDP derivatives.	2009 Sep	19523433
Lipase-catalyzed reactions at interfaces of two-phase systems and microemulsions.	2009 Sep	18795240
Enzymatic synthesis of Mycoplasma fermentans specific glycoglycerophospholipid from 1,2-dipalmitoylglycerol.	2010 Apr	20226374

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

The methanolic extract of the of Carica papaya L. (Caricaceae) (glyceryl-1,2-dipalmitate is a component of the seeds) (200 μg/ml) showed antifungal activity against Aspergillus flavus, Candida albicans and Penicillium citrinium.

Substance Class	Chemical Created by `admin` on `Fri Dec 15 19:42:11 UTC 2023` Edited by `admin` on `Fri Dec 15 19:42:11 UTC 2023`
Record UNII	R7P33H2T7C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

GLYCERYL 1,2-DIPALMITATE

Common Name

English

1,2-DIPALMITIN

Common Name

English

DL-1,2-DIPALMITIN

Common Name

English

1,2-DIPALMITOYL-RAC-GLYCEROL

Common Name

English

RAC-GLYCEROL 1,2-DIPALMITATE

Common Name

English

(±)-1,2-DIPALMITIN

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

254-870-3