Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C20H25N3O |
| Molecular Weight | 323.432 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(C)CC(C)(C)C1=CC(N2N=C3C=CC=CC3=N2)=C(O)C=C1
InChI
InChIKey=IYAZLDLPUNDVAG-UHFFFAOYSA-N
InChI=1S/C20H25N3O/c1-19(2,3)13-20(4,5)14-10-11-18(24)17(12-14)23-21-15-8-6-7-9-16(15)22-23/h6-12,24H,13H2,1-5H3
| Molecular Formula | C20H25N3O |
| Molecular Weight | 323.432 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Octrizole (UV-329) is used as UV stabilizer
within products to increase stability to light. It protects polymers as well as organic pigments from UV radiation helping to preserve the original appearance and physical integrity of polymeric systems; particularly in polyesters, polyvinyl chlorides, styrenics, acrylics, polycarbonates and polyvinyl butyral during outdoor weathering. Octrizole is an indirect additive used in food contact substances. It is
used in cosmetics. The use levels of Octrizole (UV-329) range between 0.10 and 1.0%, depending on substrate
and performance requirements of the final application. The product can be used
alone or in combination with other additives such as light stabilizers (hindered
amines), antioxidants (hindered phenols, phosphites, thiosynergists,
hydroxylamines, benzofuranones), and other functional stabilizers and
additives. The use of UV-329 in combination with hindered amine light stabilizers
is particularly noteworthy in that a synergistic performance is often observed.
Performance data of UV- 329 alone or in combination with other additives are
available in selected substrates.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | 2006-11 |
|
| Prediction of genotoxicity of chemical compounds by statistical learning methods. | 2005-06 |
|
| Steroid hormone activity of flavonoids and related compounds. | 2000-07 |
Sample Use Guides
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/28486152
Putative thyroid disrupting effect of UV-329 (Octrizole) was studied in zebrafish embryos at 1, 10 and 100 ug/L for 96 h.
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 18:24:34 GMT 2025
by
admin
on
Mon Mar 31 18:24:34 GMT 2025
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| Record UNII |
R775Y233N3
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Validated (UNII)
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C851
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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PARENT -> IMPURITY |
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |