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Details

Stereochemistry ACHIRAL
Molecular Formula C25H34F3N5O2
Molecular Weight 493.5659
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of ABT-384

SMILES

CC(C)(C(=N[C@@]1([H])C2([H])CC3([H])CC1([H])C[C@@](C3)(C2)C(=N)O)O)N4CCN(CC4)c5ccc(cn5)C(F)(F)F

InChI

InChIKey=CLHMYBJIOZXCEX-MALZWFGSSA-N
InChI=1S/C25H34F3N5O2/c1-23(2,33-7-5-32(6-8-33)19-4-3-18(14-30-19)25(26,27)28)22(35)31-20-16-9-15-10-17(20)13-24(11-15,12-16)21(29)34/h3-4,14-17,20H,5-13H2,1-2H3,(H2,29,34)(H,31,35)/t15?,16?,17?,20-,24+

HIDE SMILES / InChI

Molecular Formula C25H34F3N5O2
Molecular Weight 493.5659
Charge 0
Count
Stereochemistry MIXED
Additional Stereochemistry No
Defined Stereocenters 1 / 3
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Substance Class Chemical
Created
by admin
on Sat Jun 26 14:57:10 UTC 2021
Edited
by admin
on Sat Jun 26 14:57:10 UTC 2021
Record UNII
R5TH77F919
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ABT-384
Common Name English
Code System Code Type Description
DRUG BANK
DB12501
Created by admin on Sat Jun 26 14:57:11 UTC 2021 , Edited by admin on Sat Jun 26 14:57:11 UTC 2021
PRIMARY
PUBCHEM
11670435
Created by admin on Sat Jun 26 14:57:11 UTC 2021 , Edited by admin on Sat Jun 26 14:57:11 UTC 2021
PRIMARY
FDA UNII
R5TH77F919
Created by admin on Sat Jun 26 14:57:11 UTC 2021 , Edited by admin on Sat Jun 26 14:57:11 UTC 2021
PRIMARY
CAS
868623-40-9
Created by admin on Sat Jun 26 14:57:11 UTC 2021 , Edited by admin on Sat Jun 26 14:57:11 UTC 2021
PRIMARY
Related Record Type Details
METABOLIC ENZYME -> SUBSTRATE
METABOLIC ENZYME -> SUBSTRATE
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ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC IN HEALTHY VOLUNTEERS

SINGLE DOSE ADMINISTRATION

Biological Half-life PHARMACOKINETIC IN HEALTHY VOLUNTEERS

SINGLE DOSE ADMINISTRATION

Tmax PHARMACOKINETIC IN HEALTHY VOLUNTEERS

SINGLE DOSE ADMINISTRATION

Tmax PHARMACOKINETIC IN HEALTHY VOLUNTEERS

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