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Details

Stereochemistry ACHIRAL
Molecular Formula C36H62N4.2C7H5NO3S
Molecular Weight 917.2773
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of OCTENIDINE SACCHARIN

SMILES

CCCCCCCCN=c1ccn(CCCCCCCCCCn2ccc(=NCCCCCCCC)cc2)cc1.c1ccc2c(c1)C(=NS2(=O)=O)O.c1ccc2c(c1)C(=NS2(=O)=O)O

InChI

InChIKey=OBHFLBIBWSFADO-UHFFFAOYSA-N
InChI=1S/C36H62N4.2C7H5NO3S/c1-3-5-7-9-15-19-27-37-35-23-31-39(32-24-35)29-21-17-13-11-12-14-18-22-30-40-33-25-36(26-34-40)38-28-20-16-10-8-6-4-2;2*9-7-5-3-1-2-4-6(5)12(10,11)8-7/h23-26,31-34H,3-22,27-30H2,1-2H3;2*1-4H,(H,8,9)

HIDE SMILES / InChI

Molecular Formula C36H62N4
Molecular Weight 550.9056
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 2
Optical Activity NONE

Molecular Formula C7H5NO3S
Molecular Weight 183.1859
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Octenidine dihydrochloride is a cationic surfactant, with antimicrobial activity against Gram-positive and Gram-negative bacteria. Octenidine approved as a medicinal substance in several European countries and used for skin antisepsis in combination with aliphatic alcohols, e.g. propan-1-ol and propan-2-ol, or with detergents such as antiseptic soap. Octenidine is also used for antisepsis on wounds and mucosa either as a single substance, as an approved combination of Octenidine and phenoxyethanol. Octenidine is virtually not absorbed via the skin or mucous membranes. Because Octenidine is only approved and used topically and is virtually not absorbed, no systemic effects are to be expected. Therefore, no further pharmacokinetic studies or studies on behalf of metabolism have been conducted. Octenidine is easy and safe to handle, chemically stable, not inflammable, without resistance development and low toxicity to man and the environment alike. Its popularity among therapists and wound care specialists is based on good clinical results, easy and pain-free application and local tolerance. Beside readily available combinations with phenoxyethanol, mouth rinses, and vaginal applications, semi-fluid preparations and dressings are described.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
Target ID: Plasma membrane of Microorganisms
Patents

Patents

Substance Class Chemical
Created
by admin
on Sat Jun 26 06:54:51 UTC 2021
Edited
by admin
on Sat Jun 26 06:54:51 UTC 2021
Record UNII
R337868TDW
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
OCTENIDINE SACCHARIN
USAN  
USAN  
Official Name English
1-OCTANAMINE, N,N'-(1,10-DECANEDIYLDI-1(4H)-PYRIDINYL-4-YLIDENE)BIS-, COMPOUND WITH 1,2-BENZISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE (1:2)
Common Name English
OCTENIDINE SACCHARIN [USAN]
Common Name English
OCTENIDINE DISACCHARIN [MI]
Common Name English
WIN 41,464-6
Code English
WIN-41464-6
Code English
1,1'-DECAMETHYLENEBIS(1,4-DIHYDRO-4-(OCTYLIMINO)PYRIDINE) COMPOUND WITH 1,2-BENZISOTHIAZOLIN-3-ONE 1,1-DIOXIDE (1:2)
Common Name English
OCTENIDINE DISACCHARIN
MI  
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C28394
Created by admin on Sat Jun 26 06:54:51 UTC 2021 , Edited by admin on Sat Jun 26 06:54:51 UTC 2021
Code System Code Type Description
PUBCHEM
3047799
Created by admin on Sat Jun 26 06:54:51 UTC 2021 , Edited by admin on Sat Jun 26 06:54:51 UTC 2021
PRIMARY
NCI_THESAURUS
C80861
Created by admin on Sat Jun 26 06:54:51 UTC 2021 , Edited by admin on Sat Jun 26 06:54:51 UTC 2021
PRIMARY
CAS
86767-75-1
Created by admin on Sat Jun 26 06:54:51 UTC 2021 , Edited by admin on Sat Jun 26 06:54:51 UTC 2021
PRIMARY
ChEMBL
CHEMBL1199480
Created by admin on Sat Jun 26 06:54:51 UTC 2021 , Edited by admin on Sat Jun 26 06:54:51 UTC 2021
PRIMARY
EPA CompTox
86767-75-1
Created by admin on Sat Jun 26 06:54:51 UTC 2021 , Edited by admin on Sat Jun 26 06:54:51 UTC 2021
PRIMARY
MERCK INDEX
M8113
Created by admin on Sat Jun 26 06:54:51 UTC 2021 , Edited by admin on Sat Jun 26 06:54:51 UTC 2021
PRIMARY Merck Index
FDA UNII
R337868TDW
Created by admin on Sat Jun 26 06:54:51 UTC 2021 , Edited by admin on Sat Jun 26 06:54:51 UTC 2021
PRIMARY
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