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Details

Stereochemistry ACHIRAL
Molecular Formula C10H6O4.C4H11N
Molecular Weight 263.2896
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CHROMOCARB DIETHYLAMINE

SMILES

c1ccc2c(c1)c(=O)cc(C(=O)O)o2.CCNCC

InChI

InChIKey=BTDWBTIPKMIUHM-UHFFFAOYSA-N
InChI=1S/C10H6O4.C4H11N/c11-7-5-9(10(12)13)14-8-4-2-1-3-6(7)8;1-3-5-4-2/h1-5H,(H,12,13);5H,3-4H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C4H11N
Molecular Weight 73.137
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C10H6O4
Molecular Weight 190.1526
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Chromocarb is benzo-γ-pyrone derivative with vasoprotection activity used to eliminate lipoperoxidation post-vitrectomy. Peroral treatment of rats with chromocarb significantly reduced the degradation of the vascular wall by intravenous collagenase, as demonstrated by a lesser permeability increase of the blood-brain barrier, a shorter recovery time, lower hydroxyproline levels in the cerebrospinal fluid and a lesser decrease of the collagen content of the brain capillary basal lamina.

Originator

Sources: Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen (1933), 66B, 1168-77.

Approval Year

Targets

Targets

Primary TargetPharmacologyConditionPotency
PubMed

PubMed

TitleDatePubMed
Chromone-2- and -3-carboxylic acids inhibit differently monoamine oxidases A and B.
2010 May 1
Patents

Sample Use Guides

rats: 50 mg/kg daily in drinking water for 30 days
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Jun 26 15:24:22 UTC 2021
Edited
by admin
on Sat Jun 26 15:24:22 UTC 2021
Record UNII
R0O8TF63DH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CHROMOCARB DIETHYLAMINE
MART.   MI   WHO-DD  
Common Name English
CHROMOCARB DIETHYLAMINE [MI]
Common Name English
4-OXO-4H-1-BENZOPYRAN-2-CARBOXYLIC ACID COMPD. WITH N-ETHYLETHANAMINE (1:1)
Systematic Name English
CHROMOCARB DIETHYLAMINE [MART.]
Common Name English
DIETHYLAMINE, 4-OXO-4H-1-BENZOPYRAN-2-CARBOXYLATE
Systematic Name English
ETHANAMINE, N-ETHYL-, 4-OXO-4H-1-BENZOPYRAN-2-CARBOXYLATE
Systematic Name English
4H-1-BENZOPYRAN-2-CARBOXYLIC ACID, 4-OXO-, COMPD. WITH N-ETHYLETHANAMINE (1:1)
Common Name English
FLUDARENE
Common Name English
N,N-DIETHYLAMMONIUM CHROMONE-2-CARBOXYLATE
Systematic Name English
CHROMOCARB DIETHYLAMINE [WHO-DD]
Common Name English
Code System Code Type Description
RXCUI
48064
Created by admin on Sat Jun 26 15:24:22 UTC 2021 , Edited by admin on Sat Jun 26 15:24:22 UTC 2021
PRIMARY RxNorm
EPA CompTox
23915-80-2
Created by admin on Sat Jun 26 15:24:22 UTC 2021 , Edited by admin on Sat Jun 26 15:24:22 UTC 2021
PRIMARY
FDA UNII
R0O8TF63DH
Created by admin on Sat Jun 26 15:24:22 UTC 2021 , Edited by admin on Sat Jun 26 15:24:22 UTC 2021
PRIMARY
PUBCHEM
159960
Created by admin on Sat Jun 26 15:24:22 UTC 2021 , Edited by admin on Sat Jun 26 15:24:22 UTC 2021
PRIMARY
MERCK INDEX
M3511
Created by admin on Sat Jun 26 15:24:22 UTC 2021 , Edited by admin on Sat Jun 26 15:24:22 UTC 2021
PRIMARY Merck Index
EVMPD
SUB01284MIG
Created by admin on Sat Jun 26 15:24:22 UTC 2021 , Edited by admin on Sat Jun 26 15:24:22 UTC 2021
PRIMARY
CAS
23915-80-2
Created by admin on Sat Jun 26 15:24:22 UTC 2021 , Edited by admin on Sat Jun 26 15:24:22 UTC 2021
PRIMARY
ECHA (EC/EINECS)
245-939-9
Created by admin on Sat Jun 26 15:24:22 UTC 2021 , Edited by admin on Sat Jun 26 15:24:22 UTC 2021
PRIMARY
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PARENT -> SALT/SOLVATE
PARENT -> SALT/SOLVATE
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ACTIVE MOIETY