CASPASE-8

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 19:57:38 GMT 2025` Edited by `admin` on `Tue Apr 01 19:57:38 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	R0EEK1NCEH
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

APOPTOTIC CYSTEINE PROTEASE

Preferred Name

English

CASPASE-8

Common Name

English

CASP-8

Common Name

English

MCH5

Common Name

English

ICE-LIKE APOPTOTIC PROTEASE 5

Common Name

English

FADD-LIKE ICE

Common Name

English

MACH

Common Name

English

APOPTOTIC PROTEASE MCH-5

Common Name

English

MORT1-ASSOCIATED CED-3 HOMOLOG

Common Name

English

CAP4

Common Name

English

FADD-HOMOLOGOUS ICE/CED-3-LIKE PROTEASE

Common Name

English

FLICE

Common Name

English

Code System Code Type Description

UNIPROT

Q14790

Created by admin on Tue Apr 01 19:57:38 GMT 2025 , Edited by admin on Tue Apr 01 19:57:38 GMT 2025

PRIMARY

WIKIPEDIA

CASPASE_8

Created by admin on Tue Apr 01 19:57:38 GMT 2025 , Edited by admin on Tue Apr 01 19:57:38 GMT 2025

PRIMARY

PHAROS

Q14790

Created by admin on Tue Apr 01 19:57:38 GMT 2025 , Edited by admin on Tue Apr 01 19:57:38 GMT 2025

PRIMARY

FDA UNII

R0EEK1NCEH

Created by admin on Tue Apr 01 19:57:38 GMT 2025 , Edited by admin on Tue Apr 01 19:57:38 GMT 2025

PRIMARY

Related Record Type Details


					D0514P112G

ANISPERIMUS

ACTIVATOR -> TARGET

Amount:


					38PLP07BKC

EDRATIDE

INHIBITOR OF EXPRESSION->TARGET

Amount:


					WLA1SUY9N8

IDN-7314

INHIBITOR -> TARGET


					9554OW6MVU

NIVOCASAN

INHIBITOR -> TARGET

Amount:


					P0GMS9N47Q

EMRICASAN

INHIBITOR -> TARGET

Structural Modifications

Modification Type	Location Site	Location Type	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[2_3]	SITE_SPECIFIC	DEXFOSFOSERINE	VI4F0K069V
AMINO_ACID_SUBSTITUTION	[1_8]	SITE_SPECIFIC	N6-ACETYLLYSINE	470AD5VY1X
AMINO_ACID_SUBSTITUTION	[1_118]	SITE_SPECIFIC	TYROSINE O-PHOSPHATE	2R86C98KDX

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL