U.S. Department of Health & Human Services
National Institutes of Health
NCATS
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CASPASE-8
R0EEK1NCEH
Other
General
Record Details
Names
12
Identifiers
4
Subunits
2
Relationships
5
Modifications
3
Characteristic Attributes
2
CASPASE-8
R0EEK1NCEH
Other
General
Approval Year
Unknown
149,124
Record Details
Substance Class
Protein
Protein Sub Type
Sequence Type
COMPLETE
Record UNII
R0EEK1NCEH
Record Status
Validated (UNII)
Record Version
10
9
8
7
6
5
4
3
2
1
Names
12
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5
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entries
Name
Type
Language
Name
Type
Language
APOPTOTIC CYSTEINE PROTEASE
Preferred Name
English
CASPASE-8
Common Name
English
CASP-8
Common Name
English
MCH5
Common Name
English
ICE-LIKE APOPTOTIC PROTEASE 5
Common Name
English
Showing 1 to 5 of 12 entries
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1
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3
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Identifiers
4
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entries
Code System
Code
Type
Description
Code System
Code
Type
Description
UNIPROT
Q14790
PRIMARY
WIKIPEDIA
CASPASE_8
PRIMARY
PHAROS
Q14790
PRIMARY
FDA UNII
R0EEK1NCEH
PRIMARY
Showing 1 to 4 of 4 entries
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Subunits
2
Relationships
5
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entries
Related Record
Type
Details
Related Record
Type
Details
D0514P112G
ANISPERIMUS
ACTIVATOR -> TARGET
Amount:
38PLP07BKC
EDRATIDE
INHIBITOR OF EXPRESSION->TARGET
Amount:
WLA1SUY9N8
IDN-7314
INHIBITOR -> TARGET
9554OW6MVU
NIVOCASAN
INHIBITOR -> TARGET
Amount:
P0GMS9N47Q
EMRICASAN
INHIBITOR -> TARGET
Showing 1 to 5 of 5 entries
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Modifications
3
Structural Modifications
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entries
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
Modification Type
Location Site
Location Type
Residue Modified
Extent
Fragment Name
Fragment Approval
AMINO_ACID_SUBSTITUTION
[2_3]
SITE_SPECIFIC
DEXFOSFOSERINE
VI4F0K069V
AMINO_ACID_SUBSTITUTION
[1_8]
SITE_SPECIFIC
N6-ACETYLLYSINE
470AD5VY1X
AMINO_ACID_SUBSTITUTION
[1_118]
SITE_SPECIFIC
TYROSINE O-PHOSPHATE
2R86C98KDX
Showing 1 to 3 of 3 entries
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Characteristic Attributes
2
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entries
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Name
Property Type
Amount
Referenced Substance
Defining
Parameters
References
Molecular Formula
CHEMICAL
ESTIMATED
C1268H1980N343O394PS16
MOL_WEIGHT
CHEMICAL
Showing 1 to 2 of 2 entries
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