U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C6H4O4S.2Na
Molecular Weight 218.138
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DISODIUM P-PHENOLSULFONATE

SMILES

[Na+].[Na+].[O-]C1=CC=C(C=C1)S([O-])(=O)=O

InChI

InChIKey=XDDDDXAGOCDWDL-UHFFFAOYSA-L
InChI=1S/C6H6O4S.2Na/c7-5-1-3-6(4-2-5)11(8,9)10;;/h1-4,7H,(H,8,9,10);;/q;2*+1/p-2

HIDE SMILES / InChI
Molecular Formula Na
Molecular Weight 22.98976928
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C6H4O4S
Molecular Weight 172.159
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: http://www.ncbi.nlm.nih.gov/pubmed/3937456 and http://compoundinglab.com.au/dental-products.html

Ammonium phenolsulfonate is an ingredient of deodorant, possesses antimicrobial properties to help the inhibition of the growth of microorganism of the skin. In addition, some studies were shown, that that ammonium para-hydroxy phenyl arsonate when used with phenolsulfonates in a concentration of 0.0238% in the drinking water was effective in the prevention of hemorrhage in chicks.

Originator

Approval Year

1996
224
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Curative
Approved
8583
Negatol

Approved Use

Aphthous ulcers
PubMed

PubMed

TitleDatePubMed
Cell-transforming activity of fourteen chemical agents used in dental practice in Syrian hamster embryo cells.
2003-12
Assessment of genotoxicity of dental antiseptics: ability of phenol, guaiacol, p-phenolsulfonic acid, sodium hypochlorite, p-chlorophenol, m-cresol or formaldehyde to induce unscheduled DNA synthesis in cultured Syrian hamster embryo cells.
2000-07
Juvenilizing activity of compounds related to the juvenile hormone against pupae of the stable fly.
1972-12
Patents

Patents

20070042398
5
8227621
5
US2016066570
5
US2016068709
5
US2448029
5
US2449081
5
WO2007002194A2
5
WO2007005222A2
5

Sample Use Guides

In Vivo Use Guide
Curator's Comment: Polyphenol Sulfonic Acid Complex is Topical Solution.
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Wed Apr 02 11:35:30 GMT 2025
Edited
by admin
on Wed Apr 02 11:35:30 GMT 2025
Record UNII
R0CI3N9J8B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DISODIUM P-HYDROXYBENZENESULFONATE
Preferred Name English
DISODIUM P-PHENOLSULFONATE
Common Name English
P-HYDROXYBENZENESULFONIC ACID DISODIUM SALT
Common Name English
P-PHENOLSULFONIC ACID SODIUM SALT (1:2)
Common Name English
BENZENESULFONIC ACID, 4-HYDROXY-, DISODIUM SALT
Systematic Name English
BENZENESULFONIC ACID, P-HYDROXY-, DISODIUM SALT
Systematic Name English
BENZENESULFONIC ACID, 4-HYDROXY-, SODIUM SALT (1:2)
Systematic Name English
Code System Code Type Description
PUBCHEM
13319063
Created by admin on Wed Apr 02 11:35:30 GMT 2025 , Edited by admin on Wed Apr 02 11:35:30 GMT 2025
PRIMARY
CAS
20896-31-5
Created by admin on Wed Apr 02 11:35:30 GMT 2025 , Edited by admin on Wed Apr 02 11:35:30 GMT 2025
PRIMARY
FDA UNII
R0CI3N9J8B
Created by admin on Wed Apr 02 11:35:30 GMT 2025 , Edited by admin on Wed Apr 02 11:35:30 GMT 2025
PRIMARY
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966