U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Sat Dec 16 14:39:54 GMT 2023
Edited
by admin
on Sat Dec 16 14:39:54 GMT 2023
Source Materials Class ORGANISM
Source Materials Type AUTOLOGOUS HUMAN
Source Materials State LIVE
Source Materials Parent
Part Location metastatic melanoma
Part TUMOR
Fraction Material Type CELLS
Fraction Name TUMOR-INFILTRATING LYMPHOCYTES (TIL)
Record UNII
R0835E18NH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LIFILEUCEL
USAN   INN  
Official Name English
LIFILEUCEL [USAN]
Common Name English
TUMOR INFILTRATING LYMPHOCYTES, AUTOLOGOUS (FROM MELANOMA TUMORS)
Common Name English
LN 145 [WHO-DD]
Common Name English
lifileucel [INN]
Common Name English
AUTOLOGOUS TUMOR INFILTRATING LYMPHOCYTES
Common Name English
HUMAN CULTURE EXPANDED ACTIVATED AUTOLOGOUS T CELLS FOR CELL-BASED IMMUNOTHERAPY. THE CELL SUBSTANCE IS A HETEROGENEOUS MIXTURE CONSISTING OF CD4+ AND CD8+ TUMOR-INFILTRATING LYMPHOCYTES (TIL), DERIVED FROM ISOLATED METASTATIC TUMOR BIOPSY OF PATIENTS WI
Common Name English
LN-144
Code English
Lifileucel [WHO-DD]
Common Name English
AN AUTOLOGOUS CD4+ AND CD8+ TUMOR INFILTRATING LYMPHOCYTE, DERIVED FROM ISOLATED METASTATIC MELANOMA CULTURED IN THE PRESENCE OF FEEDER CELLS (IRRADIATED ALLOGENEIC MONONUCLEAR CELLS FROM HEALTHY DONORS), AND HUMAN RECOMBINANT INTERLEUKIN 2/MUROMONAB-CD3
Common Name English
LN-145
Code English
Code System Code Type Description
USAN
HI-45
Created by admin on Sat Dec 16 14:39:54 GMT 2023 , Edited by admin on Sat Dec 16 14:39:54 GMT 2023
PRIMARY
CAS
2306267-74-1
Created by admin on Sat Dec 16 14:39:54 GMT 2023 , Edited by admin on Sat Dec 16 14:39:54 GMT 2023
PRIMARY
INN
10728
Created by admin on Sat Dec 16 14:39:54 GMT 2023 , Edited by admin on Sat Dec 16 14:39:54 GMT 2023
PRIMARY
FDA UNII
R0835E18NH
Created by admin on Sat Dec 16 14:39:54 GMT 2023 , Edited by admin on Sat Dec 16 14:39:54 GMT 2023
PRIMARY
NCI_THESAURUS
C120552
Created by admin on Sat Dec 16 14:39:54 GMT 2023 , Edited by admin on Sat Dec 16 14:39:54 GMT 2023
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Agent Modifications

Modification Process Modification Role Modification Type Amount Fragment Name Fragment ID
CULTURE EXPANSION STIMULUS UNSPECIFIED SUBSTANCE 86fc6788
CULTURE EXPANSION STIMULUS MUROMONAB-CD3 JGA39ICE2V
CULTURE EXPANSION STIMULUS ALDESLEUKIN M89N0Q7EQR