PREDNYLIDENE 21-DIETHYLAMINOACETATE HYDROCHLORIDE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C28H39NO6.ClH
Molecular Weight	522.073
Optical Activity	UNSPECIFIED
Defined Stereocenters	7 / 7
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PREDNYLIDENE 21-DIETHYLAMINOACETATE HYDROCHLORIDE

Structure Search

SMILES

Cl.CCN(CC)CC(=O)OCC(=O)[C@@]1(O)C(=C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]12C

InChI

InChIKey=CCXTYBZGIOXYJL-DYBIKGQXSA-N

InChI=1S/C28H39NO6.ClH/c1-6-29(7-2)15-24(33)35-16-23(32)28(34)17(3)12-21-20-9-8-18-13-19(30)10-11-26(18,4)25(20)22(31)14-27(21,28)5;/h10-11,13,20-22,25,31,34H,3,6-9,12,14-16H2,1-2,4-5H3;1H/t20-,21-,22-,25+,26-,27-,28-;/m0./s1

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C28H39NO6
Molecular Weight	485.6124
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	7 / 7
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=20090326&CC=WO&NR=2009037584A2&KC=A2 | https://worldwide.espacenet.com/publicationDetails/biblio?DB=EPODOC&II=0&ND=3&adjacent=true&locale=en_EP&FT=D&date=19920729&CC=EP&NR=0496520A1&KC=A1

Prednisolone 21-diethylaminoacetate, also known as Prednisolamate, is a synthetic corticosteroid used in combination with bronchodilator for treating respiratory disease.

Approval Year

PubMed

Title	Date	PubMed
Adalimumab for the treatment of fistulas in patients with Crohn's disease.	2009-07	19201775
Lethal acute respiratory distress syndrome during anti-TNF-alpha therapy for rheumatoid arthritis.	2006-05	16200383
Transactivation via the human glucocorticoid and mineralocorticoid receptor by therapeutically used steroids in CV-1 cells: a comparison of their glucocorticoid and mineralocorticoid properties.	2004-09	15362971
11beta-hydroxysteroid dehydrogenase types 1 and 2: an important pharmacokinetic determinant for the activity of synthetic mineralo- and glucocorticoids.	2002-12	12466373

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:21:52 GMT 2025` Edited by `admin` on `Mon Mar 31 22:21:52 GMT 2025`
Record UNII	QZU7V4G1RX
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PREDNYLIDENE 21-DIETHYLAMINOACETATE HYDROCHLORIDE

Common Name

English

16-METHYLENEPREDNISOLONE-21-DIETHYLAMINOACETATE HYDROCHLORIDE

Preferred Name

English

PREDNYLIDENE 21-DIETHYLAMINOACETATE HYDROCHLORIDE [MI]

Common Name

English

GLYCINE, N,N-DIETHYL-, (11.BETA.)-11,17-DIHYDROXY-16-METHYLENE-3,20-DIOXOPREGNA-1,4-DIEN-21-YL ESTER, HYDROCHLORIDE

Common Name

English

Code System Code Type Description

ECHA (EC/EINECS)

245-299-0