Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C21H26N8O4 |
| Molecular Weight | 454.4823 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
COC1=C2N=C(NC(=O)C3=CN=C(N)N=C3)N4CCN=C4C2=CC=C1OCCCNCCO
InChI
InChIKey=MRKSMBKRMJMBJR-UHFFFAOYSA-N
InChI=1S/C21H26N8O4/c1-32-17-15(33-10-2-5-23-7-9-30)4-3-14-16(17)27-21(29-8-6-24-18(14)29)28-19(31)13-11-25-20(22)26-12-13/h3-4,11-12,23,30H,2,5-10H2,1H3,(H2,22,25,26)(H,27,28,31)
| Molecular Formula | C21H26N8O4 |
| Molecular Weight | 454.4823 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 1 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:21:06 GMT 2023
by
admin
on
Sat Dec 16 14:21:06 GMT 2023
|
| Record UNII |
QYB71X85N4
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
2132943-81-6
Created by
admin on Sat Dec 16 14:21:06 GMT 2023 , Edited by admin on Sat Dec 16 14:21:06 GMT 2023
|
PRIMARY | |||
|
QYB71X85N4
Created by
admin on Sat Dec 16 14:21:06 GMT 2023 , Edited by admin on Sat Dec 16 14:21:06 GMT 2023
|
PRIMARY | |||
|
130420807
Created by
admin on Sat Dec 16 14:21:06 GMT 2023 , Edited by admin on Sat Dec 16 14:21:06 GMT 2023
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
PARENT -> METABOLITE |
(DEALKYLATION BY CYP3A4), The six healthy male volunteers received a single i.v. infusion of 12 mg copanlisib (2.76 MBq (14C)copanlisib) in a total volume of 40 mL as a 1-h infusion in the morning, 1-h after a light breakfast. 5 Caucasians and 1 Asian with an age 54.8 +/- 5.2 yeas (mean +/- SD, range: 47-61 years) and a BMI of 24.8 kg/m^2. Non-smokers and reported at the most light alcohol use.
AMOUNT EXCRETED
FECAL
|
