U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 22:01:55 GMT 2025
Edited
by admin
on Tue Apr 01 22:01:55 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
QXN20J93AH
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
VOPRATELIMAB
USAN   INN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(INDUCIBLE T-CELL COSTIMULATOR)(HUMANIZED MONOCLONAL JTX-2011 .GAMMA.1-CHAIN), DISULFIDE WITH HUMANIZED MONOCLONAL JTX-2011 .KAPPA.-CHAIN, DIMER
Preferred Name English
VOPRATELIMAB [USAN]
Common Name English
vopratelimab [INN]
Common Name English
Vopratelimab [WHO-DD]
Common Name English
IMMUNOGLOBULIN G1-KAPPA, ANTI-( HOMO SAPIENS INDUCIBLE T-CELL COSTIMULATOR (ANTIGEN CD278))HUMANIZED MONOCLONAL ANTIBODY.GAMMA.1 HEAVY CHAIN (1-447) (HUMANIZED VH (HOMO SAPIENS IGHV3-74*01 (89%) (IGHD)-IGHJ5*01) (8.8.10) (1-117)-HOMO SAPIENS IGHG1*03 (CH
Systematic Name English
JTX-2011
Code English
ANTI-ICOS AGONIST MAB JTX-2011
Common Name English
ANTI-ICOS AGONIST MONOCLONAL ANTIBODY JTX-2011
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C141145
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
NCI_THESAURUS C129822
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
Code System Code Type Description
USAN
FG-61
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
PRIMARY
FDA UNII
QXN20J93AH
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
PRIMARY
NCI_THESAURUS
C129876
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
PRIMARY
INN
10730
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
PRIMARY
DRUG BANK
DB15378
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
PRIMARY
CAS
2039148-04-2
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
PRIMARY
SMS_ID
100000181742
Created by admin on Tue Apr 01 22:01:55 GMT 2025 , Edited by admin on Tue Apr 01 22:01:55 GMT 2025
PRIMARY
From To
1_22 1_96
1_144 1_200
1_261 1_321
1_367 1_425
2_22 2_96
2_144 2_200
2_261 2_321
2_367 2_425
1_226 2_226
1_229 2_229
1_220 3_218
2_220 4_218
3_23 3_92
3_138 3_198
4_23 4_92
4_138 4_198
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_297
N 2_297
Related Record Type Details
INDUCIBLE T-CELL COSTIMULATOR
TARGET -> AGONIST
Related Record Type Details
VOPRATELIMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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