Vimekofusp

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 06:40:28 GMT 2025` Edited by `admin` on `Wed Apr 02 06:40:28 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	QX77JY19LD
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AMT-101

Preferred Name

English

Vimekofusp

Official Name

English

Recombinant human interleukin-10 fusion protein

Common Name

English

1-386-Cholix toxin [methionyl,3-glutamic acid,4-alanine] (Vibrio cholerae clone AMT-101 gene chxA) fusion protein with peptide linker ((GGGGS)2GGGG) fusion protein with interleukin 10 (human), monomer

Common Name

English

Vibrio cholerae L -methionyl-cholix toxin (exotoxin A, NAD(+)-diphthamide ADP-ribosyltransferase, EC: 2.4.2.36), fragment (1-386, 2-387 in the current sequence), variant (D<sup>3</sup> >E <sup>4</sup>, E <sup>4</sup>>A <sup>5</sup>), fused via peptide li

Common Name

English

vimekofusp [INN]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

784420

Created by admin on Wed Apr 02 06:40:28 GMT 2025 , Edited by admin on Wed Apr 02 06:40:28 GMT 2025

Code System Code Type Description

CAS

2771192-33-5

Created by admin on Wed Apr 02 06:40:28 GMT 2025 , Edited by admin on Wed Apr 02 06:40:28 GMT 2025

PRIMARY

FDA UNII

QX77JY19LD

Created by admin on Wed Apr 02 06:40:28 GMT 2025 , Edited by admin on Wed Apr 02 06:40:28 GMT 2025

PRIMARY

SMS_ID

300000015763

Created by admin on Wed Apr 02 06:40:28 GMT 2025 , Edited by admin on Wed Apr 02 06:40:28 GMT 2025

PRIMARY

INN

12800

Created by admin on Wed Apr 02 06:40:28 GMT 2025 , Edited by admin on Wed Apr 02 06:40:28 GMT 2025

PRIMARY

https://extranet.who.int/soinn/mod/page/view.php?id=137&inn_n=12800

NCI_THESAURUS

C203052

Created by admin on Wed Apr 02 06:40:28 GMT 2025 , Edited by admin on Wed Apr 02 06:40:28 GMT 2025

PRIMARY

From	To
2_463	2_515
2_413	2_509
2_279	2_301
2_209	2_226
2_12	2_16
1_463	1_515
1_413	1_509
1_279	1_301
1_209	1_226
1_12	1_16

Related Record Type Details


					51F8I2CLT3

SIGNAL TRANSDUCER AND ACTIVATOR OF TRANSCRIPTION 3

TARGET -> ACTIVATOR

Amount:

Related Record Type Details


					QX77JY19LD

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
LINKER PEPTIDE	PROTEIN FEATURE
Molecular Formula	CHEMICAL
LINKER PEPTIDE	PROTEIN FEATURE
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL