Sigvotatug vedotin

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 15:45:27 UTC 2023` Edited by `admin` on `Sat Dec 16 15:45:27 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED
Sequence Type	COMPLETE
Record UNII	QX0ONY0O9T
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Sigvotatug vedotin

Official Name

English

Immunoglobulin G1, anti-(human integrin β6) (human-Mus musculus monoclonal h2A2 γ1-chain), disulfide with human-Mus musculus monoclonal h2A2 κ-chain, dimer, reduced, tetrakis(thioether) with N-[[[4-[[N-[6-(3-mercapto-2,5-dioxo-1-pyrrolidinyl)-1-oxohex

Common Name

English

sigvotatug vedotin [INN]

Common Name

English

Immunoglobulin G1-kappa, anti-[Homo sapiens ITGB6 (integrin subunit beta 6)], humanized monoclonal antibody, conjugated on an average of 4 cysteinyl residues via a cleavable linker to monomethylauristatin E (MMAE)

Common Name

English

Code System Code Type Description

FDA UNII

QX0ONY0O9T

Created by admin on Sat Dec 16 15:45:28 UTC 2023 , Edited by admin on Sat Dec 16 15:45:28 UTC 2023

PRIMARY

CAS

2764774-91-4

Created by admin on Sat Dec 16 15:45:28 UTC 2023 , Edited by admin on Sat Dec 16 15:45:28 UTC 2023

PRIMARY

INN

12757

Created by admin on Sat Dec 16 15:45:28 UTC 2023 , Edited by admin on Sat Dec 16 15:45:28 UTC 2023

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_366	2_424
2_260	2_320
2_219	4_214
2_143	2_199
2_22	2_96
1_366	1_424
1_260	1_320
1_228	2_228
1_225	2_225
1_219	3_214
1_143	1_199
1_22	1_96