MELANOCORTIN RECEPTOR 3

Approval Year

Substance Class	Protein
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	QV1Q1KK8LA
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MELANOCORTIN RECEPTOR 3

Common Name

English

MC3-R

Common Name

English

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Code System

Code

Type

Description

FDA UNII

QV1Q1KK8LA

PRIMARY

UNIPROT

P41968

PRIMARY

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Subunit 0

Glycosylation Type

HUMAN

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Glycosylation Link Type	Site
N	1_2
N	1_16
N	1_28

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Related Record

Type

Details


					WF3QYF69YU

PF-07258669

INHIBITOR -> TARGET

Interaction Type:

BINDING

Qualification:

Ki

Amount:

340 (average)


					UPF5CJ93X7

MELANOTAN II

AGONIST -> TARGET

Qualification:

Ki

Amount:

34 NANOMOLAR (average)


					6Y24O4F92S

BREMELANOTIDE

AGONIST -> TARGET

Amount:


					96C1EBE9CG

MODIMELANOTIDE

AGONIST -> TARGET

Amount:


					WF3QYF69YU

PF-07258669

INHIBITOR -> TARGET

Comments:

Ability to block α-MSH-induced cAMP production in a CHO cell line expressing hMC3R.

Interaction Type:

BIOASSAY (CELLULAR)

Qualification:

Ki

Amount:

97 NANOMOLAR (average)

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL

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