Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C15H13N3O2.C6H15NO3 |
| Molecular Weight | 416.4708 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OCCN(CCO)CCO.CN1C=CC=C1C(=O)C(C#N)C(=O)NC2=CC=CC=C2
InChI
InChIKey=HZXCDXNTMAAZIL-UHFFFAOYSA-N
InChI=1S/C15H13N3O2.C6H15NO3/c1-18-9-5-8-13(18)14(19)12(10-16)15(20)17-11-6-3-2-4-7-11;8-4-1-7(2-5-9)3-6-10/h2-9,12H,1H3,(H,17,20);8-10H,1-6H2
| Molecular Formula | C6H15NO3 |
| Molecular Weight | 149.1882 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C15H13N3O2 |
| Molecular Weight | 267.2826 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Prinomide is a carbamoylpyrrolepropionitrile derivative patented by Ciba-Geigy A.-G. as a nonsteroidal anti-inflammatory drug that has disease-modifying activity in rheumatoid arthritis. In clinical trials, Prinomide demonstrate significant improvement in symptom score and laboratory variables.
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Prinomide tromethamine pharmacokinetics: mutually dependent saturable and competitive protein binding between prinomide and its own metabolite. | 1993-01 |
|
| Effect of a new antirheumatic drug (CGS10787B) on antibody formation and delayed-type hypersensitivity in BALB/c mice. | 1988 |
Patents
| Substance Class |
Chemical
Created
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Mon Mar 31 17:33:58 GMT 2025
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Mon Mar 31 17:33:58 GMT 2025
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| Record UNII |
QS47I8M51B
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| Record Status |
Validated (UNII)
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DTXSID20998859
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77639-70-4
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QS47I8M51B
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admin on Mon Mar 31 17:33:58 GMT 2025 , Edited by admin on Mon Mar 31 17:33:58 GMT 2025
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