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Details

Stereochemistry RACEMIC
Molecular Formula C15H13N3O2.C6H15NO3
Molecular Weight 416.4716
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of PRINOMIDE TROLAMINE

SMILES

Cn1cccc1C(=O)C(C#N)C(=Nc2ccccc2)O.C(CO)N(CCO)CCO

InChI

InChIKey=HZXCDXNTMAAZIL-UHFFFAOYSA-N
InChI=1S/C15H13N3O2.C6H15NO3/c1-18-9-5-8-13(18)14(19)12(10-16)15(20)17-11-6-3-2-4-7-11;8-4-1-7(2-5-9)3-6-10/h2-9,12H,1H3,(H,17,20);8-10H,1-6H2

HIDE SMILES / InChI

Molecular Formula C6H15NO3
Molecular Weight 149.1884
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C15H13N3O2
Molecular Weight 267.2832
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Prinomide is a carbamoylpyrrolepropionitrile derivative patented by Ciba-Geigy A.-G. as a nonsteroidal anti-inflammatory drug that has disease-modifying activity in rheumatoid arthritis. In clinical trials, Prinomide demonstrate significant improvement in symptom score and laboratory variables.

Approval Year

PubMed

PubMed

TitleDatePubMed
Patents

Patents

Sample Use Guides

250, 500, and 1000 mg every 12 hr for 28 days to healthy male volunteers.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Sat Jun 26 11:25:21 UTC 2021
Edited
by admin
on Sat Jun 26 11:25:21 UTC 2021
Record UNII
QS47I8M51B
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PRINOMIDE TROLAMINE
Common Name English
CGS-10787B
Common Name English
ETHANOL, 2,2',2''-NITRILOTRIS-, COMPD. WITH .ALPHA.-CYANO-1-METHYL-.BETA.-OXO-N-PHENYL-1H-PYRROLE-2-PROPANAMIDE (1:1)
Systematic Name English
Code System Code Type Description
PUBCHEM
127553
Created by admin on Sat Jun 26 11:25:21 UTC 2021 , Edited by admin on Sat Jun 26 11:25:21 UTC 2021
PRIMARY
CAS
77639-70-4
Created by admin on Sat Jun 26 11:25:21 UTC 2021 , Edited by admin on Sat Jun 26 11:25:21 UTC 2021
PRIMARY
FDA UNII
QS47I8M51B
Created by admin on Sat Jun 26 11:25:21 UTC 2021 , Edited by admin on Sat Jun 26 11:25:21 UTC 2021
PRIMARY
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ACTIVE MOIETY