MICROTUBULE-ASSOCIATED PROTEIN TAU (PAIRED HELICAL FILAMENTS (PHF))

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 21:43:03 GMT 2025` Edited by `admin` on `Mon Mar 31 21:43:03 GMT 2025`
Protein Type	AGGREGATED PROTEIN
Protein Sub Type	TAU
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	QR9EFE0TG6
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MICROTUBULE-ASSOCIATED PROTEIN TAU (PAIRED HELICAL FILAMENTS (PHF))

Common Name

English

NEUROFIBRILLARY TANGLE PROTEIN (PHF)

Preferred Name

English

PHF-TAU

Common Name

English

TAU hyperphosphorylated NFT protein

Common Name

English

PAIRED HELICAL FILAMENT-TAU

Common Name

English

Code System Code Type Description

FDA UNII

QR9EFE0TG6

Created by admin on Mon Mar 31 21:43:03 GMT 2025 , Edited by admin on Mon Mar 31 21:43:03 GMT 2025

PRIMARY

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
O	1_524
O	1_554
O	1_716

Related Record Type Details


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Comments:

inhibits the spread of tau tangles


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Amount:


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Interaction Type:

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Amount:


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Qualification:

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Amount:


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Comments:

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Amount:


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Amount:


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Comments:

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Amount:


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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1]	N-TERMINUS	ALANINE	Amount:	N-ACETYLALANINE	26C4VY6Z0M
AMINO_ACID_SUBSTITUTION			SERINE	Amount:	DEXFOSFOSERINE	VI4F0K069V
AMINO_ACID_SUBSTITUTION	[1_17] [1_28] [1_196] [2_17] [2_28] [2_196] [3_17] [3_28] [3_196]		Y	Amount:	3-NITRO-L-TYROSINE	7COY1HA6HK
AMINO_ACID_SUBSTITUTION				Amount:	THREONINE PHOSPHATE	3L4WX7B1EI

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL