U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 07:38:46 GMT 2023
Edited
by admin
on Sat Dec 16 07:38:46 GMT 2023
Protein Type AGGREGATED PROTEIN
Protein Sub Type TAU
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
QR9EFE0TG6
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MICROTUBULE-ASSOCIATED PROTEIN TAU (PAIRED HELICAL FILAMENTS (PHF))
Common Name English
PHF-TAU
Common Name English
TAU hyperphosphorylated NFT protein
Common Name English
NEUROFIBRILLARY TANGLE PROTEIN (PHF)
Common Name English
PAIRED HELICAL FILAMENT-TAU
Common Name English
Code System Code Type Description
FDA UNII
QR9EFE0TG6
Created by admin on Sat Dec 16 07:38:46 GMT 2023 , Edited by admin on Sat Dec 16 07:38:46 GMT 2023
PRIMARY
Glycosylation Type HUMAN
Glycosylation Link Type Site
O 1_524
O 1_554
O 1_716
Related Record Type Details
INHIBITOR OF AGGREGATION->TARGET
inhibits the spread of tau tangles
INHIBITOR -> TARGET
LIGAND->TARGET
Designed to bind to and neutralize tau clumps, slowing or stopping the worsening of Alzheimer’s.
RADIOLIGAND->TARGET
RADIOLIGAND->TARGET
Images aggregates
INHIBITOR OF AGGREGATION->TARGET
INHIBITOR OF AGGREGATION->TARGET
RADIOLIGAND->TARGET
RADIOLIGAND->TARGET
RADIOLIGAND->TARGET
RADIOLIGAND->TARGET
INHIBITOR OF EXPRESSION->TARGET
PRECLINICAL
LIGAND->TARGET
TARGET->RADIOLIGAND
Kd
INHIBITOR OF AGGREGATION->TARGET
Recognizes an aggregated, extracellular form of pathological tau.
RADIOLIGAND->TARGET
RADIOLIGAND->TARGET
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL