DRESBUXELIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 11:28:58 GMT 2025` Edited by `admin` on `Wed Apr 02 11:28:58 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Type	COMPLETE
Record UNII	QR3A4G4VHU
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DRESBUXELIMAB

Official Name

English

AK 119 [WHO-DD]

Preferred Name

English

IMMUNOGLOBULIN G1, ANTI-(HUMAN 5'-NUCLEOTIDASE) (HUMAN-MUS MUSCULUS MONOCLONAL AK119 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL AK119 .KAPPA.-CHAIN, DIMER

Common Name

English

dresbuxelimab [INN]

Common Name

English

Code System Code Type Description

FDA UNII

QR3A4G4VHU

Created by admin on Wed Apr 02 11:28:58 GMT 2025 , Edited by admin on Wed Apr 02 11:28:58 GMT 2025

PRIMARY

CAS

2550560-20-6

Created by admin on Wed Apr 02 11:28:58 GMT 2025 , Edited by admin on Wed Apr 02 11:28:58 GMT 2025

PRIMARY

INN

12115

Created by admin on Wed Apr 02 11:28:58 GMT 2025 , Edited by admin on Wed Apr 02 11:28:58 GMT 2025

PRIMARY

SMS_ID

300000039122

Created by admin on Wed Apr 02 11:28:58 GMT 2025 , Edited by admin on Wed Apr 02 11:28:58 GMT 2025

PRIMARY

NCI_THESAURUS

C179625

Created by admin on Wed Apr 02 11:28:58 GMT 2025 , Edited by admin on Wed Apr 02 11:28:58 GMT 2025

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From	To
1_22	1_96
2_22	2_96
2_148	2_204
2_224	4_220
2_265	2_325
1_148	1_204
2_371	2_429
3_23	3_94
3_140	3_200
4_23	4_94
4_140	4_200
1_224	3_220
1_230	2_230
1_233	2_233
1_265	1_325
1_371	1_429

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_301

Related Record Type Details


					QR3A4G4VHU

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_451] [2_451]	C-TERMINUS			LYSINE	K3Z4F929H6
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS		Amount:	PIDOLIC ACID	SZB83O1W42

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER AVERAGE	CHEMICAL
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER AVERAGE	CHEMICAL