U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 11:47:31 GMT 2023
Edited
by admin
on Sat Dec 16 11:47:31 GMT 2023
Protein Sub Type
Sequence Type COMPLETE
Record UNII
QQ0IJ5P4GV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MUSCARINIC ACETYLCHOLINE RECEPTOR M5
Common Name English
CHRM5
Common Name English
M5
Common Name English
Code System Code Type Description
UNIPROT
P08912
Created by admin on Sat Dec 16 11:47:32 GMT 2023 , Edited by admin on Sat Dec 16 11:47:32 GMT 2023
PRIMARY
PHAROS
P08912
Created by admin on Sat Dec 16 11:47:32 GMT 2023 , Edited by admin on Sat Dec 16 11:47:32 GMT 2023
PRIMARY
FDA UNII
QQ0IJ5P4GV
Created by admin on Sat Dec 16 11:47:32 GMT 2023 , Edited by admin on Sat Dec 16 11:47:32 GMT 2023
PRIMARY
From To
1_103 1_183
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_8
Related Record Type Details
INHIBITOR -> TARGET
INHIBITOR -> TARGET
Ki
INHIBITOR -> TARGET
BINDING
Kd
NON-INHIBITOR->OFF TARGET
NON-INHIBITOR
Ki
INHIBITOR -> TARGET
Membranes from transfected CHO cells
BINDING
IC50
INHIBITOR -> TARGET
INHIBITOR -> TARGET
THRX-195518 possesses activity at target muscarinic receptors that was slightly lower (approximately one-third to one-tenth) than revefenacin.
BINDING
Ki
INHIBITOR -> TARGET
INHIBITOR -> TARGET
NON-INHIBITOR->OFF TARGET
AGONIST -> TARGET
ACTIVATOR -> TARGET
selective positive allosteric modulator
ALLOSTERIC ACTIVATOR
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL