U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Jun 26 23:00:29 UTC 2021
Edited
by admin
on Sat Jun 26 23:00:29 UTC 2021
Protein Sub Type
Sequence Type COMPLETE
Record UNII
QQ0IJ5P4GV
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MUSCARINIC ACETYLCHOLINE RECEPTOR M5
Common Name English
CHRM5
Common Name English
Code System Code Type Description
UNIPROT
P08912
Created by admin on Sat Jun 26 23:00:31 UTC 2021 , Edited by admin on Sat Jun 26 23:00:31 UTC 2021
PRIMARY
PHAROS
P08912
Created by admin on Sat Jun 26 23:00:31 UTC 2021 , Edited by admin on Sat Jun 26 23:00:31 UTC 2021
PRIMARY
FDA UNII
QQ0IJ5P4GV
Created by admin on Sat Jun 26 23:00:31 UTC 2021 , Edited by admin on Sat Jun 26 23:00:31 UTC 2021
PRIMARY
From To
1_103 1_183
Glycosylation Type HUMAN
Glycosylation Link Type Site
N 1_8
Related Record Type Details
ANTAGONIST->TARGET
Ki
INHIBITOR -> TARGET
BINDING
Kd
NON-INHIBITOR->OFF TARGET
NON-INHIBITOR
Ki
INHIBITOR -> TARGET
INHIBITOR -> TARGET
THRX-195518 possesses activity at target muscarinic receptors that was slightly lower (approximately one-third to one-tenth) than revefenacin.
BINDING
Ki
INHIBITOR -> TARGET
INHIBITOR -> TARGET
OFF-TARGET->NON-INHIBITOR
ACTIVATOR -> TARGET
selective positive allosteric modulator
ALLOSTERIC ACTIVATOR
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL