U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ABSOLUTE
Molecular Formula C4H4O6.K.Na.4H2O
Molecular Weight 282.2201
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of POTASSIUM SODIUM TARTRATE

SMILES

O.O.O.O.[Na+].[K+].O[C@H]([C@@H](O)C([O-])=O)C([O-])=O

InChI

InChIKey=VZOPRCCTKLAGPN-ZFJVMAEJSA-L
InChI=1S/C4H6O6.K.Na.4H2O/c5-1(3(7)8)2(6)4(9)10;;;;;;/h1-2,5-6H,(H,7,8)(H,9,10);;;4*1H2/q;2*+1;;;;/p-2/t1-,2-;;;;;;/m1....../s1

HIDE SMILES / InChI
Molecular Formula C4H6O6
Molecular Weight 150.0868
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula Na
Molecular Weight 22.9898
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula H2O
Molecular Weight 18.0153
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula K
Molecular Weight 39.0983
Charge 1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Potassium is needed to maintain good health. When potassium level falls below 3.5 mmol/L, Hypokalemia is diagnosed. In case of extremely low level of potassium (lower than 2.5 mmol/L) the following symptoms are appeared: malaise and fatigue. This low level of potassium can lead to severe muscle weakness and paralysis; respiratory failure; intermittent muscle spasms. It is known, foods that are good sources of potassium and low in sodium may reduce the risk of high blood pressure and stroke. Potassium supplementation is also recommended as an adjuvant antihypertensive agent for patients with essential hypertension.

Approval Year

1921
1447
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Palliative
Phase III
663
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Mineral and water nutrition.
1991 Jul
Age sensitivity to organophosphate-induced delayed polyneuropathy. Biochemical and toxicological studies in developing chicks.
1991 May 15
Diet, genetics and hypertension.
1997 Aug
Inhibition of HIV-1 infection by zinc group metal compounds.
1999 Sep
Delay of natural bone loss by higher intakes of specific minerals and vitamins.
2001 May
Crystal structures of Tritrichomonasfoetus inosine monophosphate dehydrogenase in complex with substrate, cofactor and analogs: a structural basis for the random-in ordered-out kinetic mechanism.
2003 Feb 14
Patents

Patents

03932629
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03956321
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03959289
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03970704
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03991176
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03991202
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03995052
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20030109560
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20030186989
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20040077867
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20040209864
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20060069144
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20060276533
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20070043040
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20080153836
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20080167356
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20080194647
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20080318874
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20090120802
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20090286768
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20100144747
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20110251176
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20110294818
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20120208817
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20130079321
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20130203732
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20130217666
23
7820025
24

Sample Use Guides

In Vivo Use Guide
Potassium is administered in various dosage forms (gluconate, citrate, chloride, bicarbonate). Exact dose should be determined by a doctor. Most people will not take more than 100 mEq a day.
Route of Administration: Oral
Substance Class Chemical
Created
by admin
on Thu Jul 06 00:00:57 UTC 2023
Edited
by admin
on Thu Jul 06 00:00:57 UTC 2023
Record UNII
QH257BPV3J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
POTASSIUM SODIUM TARTRATE
INCI   MART.   USP   USP-RS   WHO-DD  
INCI  
Official Name English
BUTANEDIOIC ACID, 2,3-DIHYDROXY-, (R-(R*,R*))-, MONOPOTASSIUM MONOSODIUM SALT, TETRAHYDRATE
Common Name English
Monopotassium monosodium tartrate tetrahydrate
Systematic Name English
E-337
Code English
POTASSIUM SODIUM TARTRATE [INCI]
Common Name English
POTASSIUM SODIUM TARTRATE TETRAHYDRATE [EP MONOGRAPH]
Common Name English
Potassium sodium tartrate [WHO-DD]
Common Name English
POTASSIUM SODIUM TARTRATE TETRAHYDRATE [MI]
Common Name English
SODIUM POTASSIUM TARTRATE [FCC]
Common Name English
INS-337
Code English
POTASSIUM SODIUM DEXTRO-TARTRATE
Common Name English
POTASSIUM SODIUM TARTRATE [USP MONOGRAPH]
Common Name English
SEIGNETTE SALT
Common Name English
ROCHELLE SALT
Common Name English
POTASSIUM SODIUM L(+)-TARTRATE
Systematic Name English
INS NO.337
Code English
SODIUM POTASSIUM TARTRATE TETRAHYDRATE [MART.]
Common Name English
SODIUM POTASSIUM TARTRATE
FCC  
Systematic Name English
POTASSIUM SODIUM TARTRATE TETRAHYDRATE
MI  
Systematic Name English
POTASSIUM SODIUM TARTRATE [MART.]
Common Name English
Classification Tree Code System Code
CFR 21 CFR 331.15
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
NCI_THESAURUS C29697
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
CODEX ALIMENTARIUS (GSFA) INS-337
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
CFR 21 CFR 331.11
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
CFR 21 CFR 184.1804
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
JECFA EVALUATION INS-337
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
Code System Code Type Description
RXCUI
1311363
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY RxNorm
NCI_THESAURUS
C80954
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
EVMPD
SUB12561MIG
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
CHEBI
63019
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
FDA UNII
QH257BPV3J
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
CAS
6100-16-9
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
SUPERSEDED
ChEMBL
CHEMBL2219738
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
WIKIPEDIA
POTASSIUM SODIUM TARTRATE
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
JECFA MONOGRAPH
INS-337
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
PUBCHEM
165453
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
EPA CompTox
DTXSID20980375
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
SMS_ID
100000078004
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
MERCK INDEX
M9060
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY Merck Index
CAS
6381-59-5
Created by admin on Thu Jul 06 00:00:58 UTC 2023 , Edited by admin on Thu Jul 06 00:00:58 UTC 2023
PRIMARY
Related Record Type Details
Structure of TARTARIC ACID
PARENT -> SALT/SOLVATE
Structure of POTASSIUM SODIUM TARTRATE ANHYDROUS
ANHYDROUS->SOLVATE
NIH
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