RIMOPROGIN

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H7IN2OS
Molecular Weight	306.123
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CSC1=NC=C(OCC#CI)C=N1

InChI

InChIKey=AKZAGHOFDGJXCC-UHFFFAOYSA-N

InChI=1S/C8H7IN2OS/c1-13-8-10-5-7(6-11-8)12-4-2-3-9/h5-6H,4H2,1H3

HIDE SMILES / InChI

Molecular Formula	C8H7IN2OS
Molecular Weight	306.123
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://patents.google.com/patent/US20040265362A1/en | https://www.ncbi.nlm.nih.gov/pubmed/782732
Curator's Comment: Referred in URI to one pubmed “title only” paper, but according to another source quality of reporting might be poor: https://books.google.com/books?id=SbsQij5xkfYC&pg=PA382&lpg=PA382&dq=klima+Report+on+clinical+experience+with+antimycotic+VUFB+9244+(Jopargin)&source=bl&ots=4zi2-mkq9D&sig=ACfU3U38SwqGNKAj9h_KNtCMerdx4XdfXA&hl=en&sa=X&ved=2ahUKEwixh4ybypHjAhWzJzQIHW8NC6YQ6AEwCXoECAUQAQ#v=snippet&q=260&f=false

Rimoprogin (VUFB-9244) is an antimycotic (antifungal) compound that was first reported in the literature in the 1970’s. It has been mentioned as a possible active agent in a plaster against dysfunctional nail growth, but there is no information on current development of rimoprogin for clinical use.

Approval Year

PubMed

Title	Date	PubMed
Antimicrobial agents. XXVI. Antifungal activity of 2-methylthio-5-(3-iodopropargyloxy)pyrimidine toward pathogenic yeast-like microorganisms.	1976	985782

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:22:04 GMT 2023` Edited by `admin` on `Fri Dec 15 16:22:04 GMT 2023`
Record UNII	QG8198SR7M
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RIMOPROGIN

Official Name

English

rimoprogin [INN]

Common Name

English

RIMOPROGIN [JAN]

Common Name

English

Rimoprogin [WHO-DD]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C514