Pumitamig

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 18:23:26 GMT 2025` Edited by `admin` on `Wed Apr 02 18:23:26 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	QEA2EG9S3E
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Pumitamig

Official Name

English

H-gamma1 heavy chain anti-VEGFA fused to a VH anti-CD274 (1-578) [Hgamma1 heavy chain anti-VEGFA humanized (1-452) [VH (Homo sapiens IGHV3-30*02 (76.8%) -(IGHD) -IGHJ4*01 (93.3%), CDR-IMGT [8.9.16] (26-33.51-59.97-112)) (1-123)-Homo sapiens IGHG1*01, G1m

Preferred Name

English

Immunoglobulin G1 [220-lysine,240-alanine,241-alanine,d-C-terminal lysine], anti-(human vascular endothelial growth factor A) (human-Mus musculus monoclonal rhuMAb-VEGF ?1-chain) fusion protein with peptide linker ((GGGS)2G) fusion protein with immunoglo

Common Name

English

pumitamig [INN]

Common Name

English

immunoglobulin (H-gamma1-VH_L-kappa) dimer, anti-[Homo sapiens VEGFA (vascular endothelial growth factor A, VEGF-A, VEGF)] and anti-[Homo sapiens CD274 (programmed cell death 1 ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, PDCD1LG1)], humanized monoc

Common Name

English

Code System Code Type Description

CAS

2999726-97-3

Created by admin on Wed Apr 02 18:23:26 GMT 2025 , Edited by admin on Wed Apr 02 18:23:26 GMT 2025

PRIMARY

FDA UNII

QEA2EG9S3E

Created by admin on Wed Apr 02 18:23:26 GMT 2025 , Edited by admin on Wed Apr 02 18:23:26 GMT 2025

PRIMARY

INN

13367

Created by admin on Wed Apr 02 18:23:26 GMT 2025 , Edited by admin on Wed Apr 02 18:23:26 GMT 2025

PRIMARY

From	To
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
2_485	2_559
2_373	2_431
2_267	2_327
2_226	4_214
2_150	2_206
2_22	2_96
1_485	1_559
1_373	1_431
1_267	1_327
1_235	2_235
1_232	2_232
1_226	3_214
1_150	1_206
1_22	1_96

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_303
N	2_303

Related Record Type Details


					QEA2EG9S3E

Pumitamig

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
MOL_WEIGHT:NUMBER AVERAGE	CHEMICAL
Molecular Formula	CHEMICAL