Baloncibart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 21:11:25 GMT 2025` Edited by `admin` on `Wed Apr 02 21:11:25 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	QCD6UJ8KWM
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

REGN-7544

Preferred Name

English

Baloncibart

Official Name

English

immunoglobulin G4-kappa, anti-[Homo sapiens NPR1 (natriuretic peptide receptor 1, natriuretic peptide receptor A, NPRA, atrionatriuretic peptide receptor A, ANPRA, guanylate cyclase A, GUCY2A)], Homo sapiens monoclonal antibody (H-gamma4 heavy chain Homo

Common Name

English

REGN7544

Code

English

Immunoglobulin G4 [228-proline], anti-(human natriuretic peptide receptor A) (human monoclonal REGN7544 ?4-chain), disulfide with human monoclonal REGN7544 ?-chain, dimer

Common Name

English

baloncibart [INN]

Common Name

English

Code System Code Type Description

FDA UNII

QCD6UJ8KWM

Created by admin on Wed Apr 02 21:11:25 GMT 2025 , Edited by admin on Wed Apr 02 21:11:25 GMT 2025

PRIMARY

INN

13486

Created by admin on Wed Apr 02 21:11:25 GMT 2025 , Edited by admin on Wed Apr 02 21:11:25 GMT 2025

PRIMARY

CAS

2988795-75-9

Created by admin on Wed Apr 02 21:11:25 GMT 2025 , Edited by admin on Wed Apr 02 21:11:25 GMT 2025

PRIMARY

From	To
1_22	1_96
2_22	2_96
2_134	4_214
2_147	2_203
2_261	2_321
1_134	3_214
2_367	2_425
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_147	1_203
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Related Record Type Details


					QCD6UJ8KWM

Baloncibart

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1]	N-TERMINUS	E		PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_447] [2_447]	C-TERMINUS	K		LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL