Details
Stereochemistry | ACHIRAL |
Molecular Formula | C19H24N2.2ClH.H2O |
Molecular Weight | 371.344 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
O.Cl.Cl.CN1CCC(CC1)N(CC2=CC=CC=C2)C3=CC=CC=C3
InChI
InChIKey=XUECZOCSQRYAQY-UHFFFAOYSA-N
InChI=1S/C19H24N2.2ClH.H2O/c1-20-14-12-19(13-15-20)21(18-10-6-3-7-11-18)16-17-8-4-2-5-9-17;;;/h2-11,19H,12-16H2,1H3;2*1H;1H2
Molecular Formula | C19H24N2 |
Molecular Weight | 280.4073 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | H2O |
Molecular Weight | 18.0153 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Molecular Formula | ClH |
Molecular Weight | 36.461 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Bamipine (trade name Soventol) is a sedating antihistamine with pronounced sedative effects. Bamipine is a pharmaceutical drug acting as an H1 antihistamine with anticholinergic properties. It is used as an antipruritic ointment. Bamipine hydrochloride has been given by mouth. Bamipine, bamipine lactate, and bamipine salicylate have all been applied topically.
Approval Year
Sample Use Guides
In Vivo Use Guide
Sources: http://www.mims.com/india/drug/info/bamipine?type=full&mtype=generic http://www.medindia.net/doctors/drug_information/bamipine.htm
Curator's Comment: Can be used topically: A thin layer applied on the surface of the skin. Re-application is possible in 30 min. Duration of treatment depends on allergic process. http://www.druginfosys.com/drug.aspx?drugcode=1567&type=1
The recommended dose is 50-100 mg 3-4 times/day.
Route of Administration:
Oral
In Vitro Use Guide
Sources: https://www.ncbi.nlm.nih.gov/pubmed/18977145
Bamipine treatment resulted in 29% of inhibition of Mycobacterium tuberculosis H37Rv (after 4 days by microplate alamar blue assay) at 6.25 ug/mL.
Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 06:34:50 GMT 2023
by
admin
on
Sat Dec 16 06:34:50 GMT 2023
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Record UNII |
QAR6L248EA
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Record Status |
Validated (UNII)
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Record Version |
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71587218
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DTXSID70212951
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admin on Sat Dec 16 06:34:51 GMT 2023 , Edited by admin on Sat Dec 16 06:34:51 GMT 2023
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Related Record | Type | Details | ||
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ANHYDROUS->SOLVATE |