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Approval Year

Unknown
139594
Substance Class Protein
Created
by admin
on Sat Dec 16 14:12:39 GMT 2023
Edited
by admin
on Sat Dec 16 14:12:39 GMT 2023
Protein Type FC FUSION PROTEIN
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
Q8A4U1Z9N2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ONTORPACEPT
INN  
Official Name English
ontorpacept [INN]
Common Name English
Ontorpacept [WHO-DD]
Common Name English
HUMAN SIGNAL-REGULATORY PROTEIN ALPHA (SIRP.ALPHA., TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE SUBSTRATE 1, INHIBITORY RECEPTOR SHPS-1), (L14>S, T20>S, T22>I, R24>H, A27>V, G45>A, D65>E, L66>S, N70>E, R77>S, G79>S, D101>DEL, V102>T101)-VARIANT, N-TER
Common Name English
1-118-SIGNAL REGULATORY PROTEIN .ALPHA. (HUMAN) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (HUMAN FC FRAGMENT), DIMER
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 624917
Created by admin on Sat Dec 16 14:12:39 GMT 2023 , Edited by admin on Sat Dec 16 14:12:39 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C125718
Created by admin on Sat Dec 16 14:12:39 GMT 2023 , Edited by admin on Sat Dec 16 14:12:39 GMT 2023
PRIMARY
CAS
1615245-83-4
Created by admin on Sat Dec 16 14:12:39 GMT 2023 , Edited by admin on Sat Dec 16 14:12:39 GMT 2023
NO STRUCTURE GIVEN
FDA UNII
Q8A4U1Z9N2
Created by admin on Sat Dec 16 14:12:39 GMT 2023 , Edited by admin on Sat Dec 16 14:12:39 GMT 2023
PRIMARY
CAS
2131089-46-6
Created by admin on Sat Dec 16 14:12:39 GMT 2023 , Edited by admin on Sat Dec 16 14:12:39 GMT 2023
PRIMARY
INN
10927
Created by admin on Sat Dec 16 14:12:39 GMT 2023 , Edited by admin on Sat Dec 16 14:12:39 GMT 2023
PRIMARY
From To
1_25 1_91
1_124 2_124
1_127 2_127
1_159 1_219
1_265 1_323
2_25 2_91
2_159 2_219
2_265 2_323
Glycosylation Link Type Site
N 1_80
N 1_195
N 2_80
N 2_195
Related Record Type Details
LEUKOCYTE SURFACE ANTIGEN CD47
TARGET -> INHIBITOR
Related Record Type Details
ONTORPACEPT
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
NIH
NCATS
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HHS VULNERABILITY DISCLOSURE
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