U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 14:05:41 GMT 2023
Edited
by admin
on Sat Dec 16 14:05:41 GMT 2023
Protein Type SIGNAL TRANSDUCER (GTPASE)
Protein Sub Type RAS
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
Q64V77I51X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GTPASE KRAS G12V MUTANT
Common Name English
KRAS G12V
Common Name English
KRAS G12V PERSISTENTLY ACTIVE MUTANT
Common Name English
Code System Code Type Description
FDA UNII
Q64V77I51X
Created by admin on Sat Dec 16 14:05:41 GMT 2023 , Edited by admin on Sat Dec 16 14:05:41 GMT 2023
PRIMARY
UNIPROT
P01116
Created by admin on Sat Dec 16 14:05:41 GMT 2023 , Edited by admin on Sat Dec 16 14:05:41 GMT 2023
PRIMARY
Related Record Type Details
INHIBITOR -> TARGET
Preferentially targets the inactive state of KRAS to prevent its reactivation by nucleotide exchange.
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL