TEMIVERINE HYDROCHLORIDE MONOHYDRATE

Details

Stereochemistry	RACEMIC
Molecular Formula	C24H35NO3.ClH.H2O
Molecular Weight	440.016
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TEMIVERINE HYDROCHLORIDE MONOHYDRATE

Structure Search

SMILES

O.Cl.CCN(CC)CC#CC(C)(C)OC(=O)C(O)(C1CCCCC1)C2=CC=CC=C2

InChI

InChIKey=FERSVTRMSSXKOL-UHFFFAOYSA-N

InChI=1S/C24H35NO3.ClH.H2O/c1-5-25(6-2)19-13-18-23(3,4)28-22(26)24(27,20-14-9-7-10-15-20)21-16-11-8-12-17-21;;/h7,9-10,14-15,21,27H,5-6,8,11-12,16-17,19H2,1-4H3;1H;1H2

HIDE SMILES / InChI

Molecular Formula	C24H35NO3
Molecular Weight	385.5396
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: Gillenwater Jay Young, Adult and Pediatric Urology, V. 1, p. 1156, retrieved from: https://books.google.ru/books?id=sCsqHg0ljoIC&pg=PA1156&lpg=PA1156&dq=TEMIVERINE+Overactive+bladder&source=bl&ots=pvonWET1Iv&sig=ACfU3U3ocEQUNo-wzEWQce88b8UTEQ4ayw&hl=ru&sa=X&ved=2ahUKEwiqxd_Z5qfjAhWPIZoKHSUgBh4Q6AEwEnoECAgQAQ#v=onepage&q=TEMIVERINE%20Overactive%20bladder&f=false | https://www.ncbi.nlm.nih.gov/pubmed/9624560

Temiverine was developed as an antimuscarinic and calcium-antagonist agent for the treatment of overactive bladder. Temiverine participated in clinical trials; however, the development of the drug was discontinued on the pre-registration stage.

Approval Year

PubMed

Title	Date	PubMed
Pharmacologic actions of temiverine (p-INN) and its active metabolite, RCC-36, on isolated human urinary bladder muscle.	1998 May	9624560

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:50:49 GMT 2023` Edited by `admin` on `Sat Dec 16 05:50:49 GMT 2023`
Record UNII	Q5WYL51TBK
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TEMIVERINE HYDROCHLORIDE MONOHYDRATE

Common Name

English

URESPAN

Brand Name

English

NS-21

Code

English

TEMIVERINE HYDROCHLORIDE HYDRATE

Common Name

English

TEMIVERINE HYDROCHLORIDE HYDRATE [JAN]

Common Name

English

5-(DIETHYLAMINO)-2-METHYL-3-PENTYN-2-YL CYCLOHEXYL(HYDROXY)PHENYLACETATE HYDROCHLORIDE HYDRATE

Systematic Name

English

BENZENEACETIC ACID, .ALPHA.-CYCLOHEXYL-.ALPHA.-HYDROXY-, 4-(DIETHYLAMINO)-1,1-DIMETHYL-2-BUTYN-1-YL ESTER, HYDROCHLORIDE, HYDRATE (1:1:1)

Common Name

English

BENZENEACETIC ACID, .ALPHA.-CYCLOHEXYL-.ALPHA.-HYDROXY-, 4-(DIETHYLAMINO)-1,1-DIMETHYL-2-BUTYNYL ESTER, HYDROCHLORIDE, MONOHYDRATE

Common Name

English

Code System Code Type Description

PUBCHEM

636417

Created by admin on Sat Dec 16 05:50:50 GMT 2023 , Edited by admin on Sat Dec 16 05:50:50 GMT 2023

PRIMARY

CAS

791115-04-3

Created by admin on Sat Dec 16 05:50:50 GMT 2023 , Edited by admin on Sat Dec 16 05:50:50 GMT 2023

PRIMARY

FDA UNII

Q5WYL51TBK

Created by admin on Sat Dec 16 05:50:50 GMT 2023 , Edited by admin on Sat Dec 16 05:50:50 GMT 2023

PRIMARY

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