Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C15H18N2O |
| Molecular Weight | 242.3162 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(C)(C)C1=CC=C(OC2=CC=C(N)C=N2)C=C1
InChI
InChIKey=WHIWGRCYMQLLAO-UHFFFAOYSA-N
InChI=1S/C15H18N2O/c1-15(2,3)11-4-7-13(8-5-11)18-14-9-6-12(16)10-17-14/h4-10H,16H2,1-3H3
| Molecular Formula | C15H18N2O |
| Molecular Weight | 242.3162 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
Cmax
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
44.4 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
13 mg single, oral dose: 13 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
53.68 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
26 mg single, oral dose: 26 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
98.47 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
52 mg single, oral dose: 52 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
367.6 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
104 mg single, oral dose: 104 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
481.63 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
148 mg single, oral dose: 148 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
731 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
217 mg single, oral dose: 217 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
1152 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
348 mg single, oral dose: 348 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
1227.38 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
522 mg single, oral dose: 522 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
1013.64 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
250 mg 2 times / day multiple, oral dose: 250 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
1631.67 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
300 mg 2 times / day multiple, oral dose: 300 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
1617.5 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
400 mg 2 times / day multiple, oral dose: 400 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
2385.63 ng/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
500 mg 2 times / day multiple, oral dose: 500 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
173.66 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
13 mg single, oral dose: 13 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
219.65 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
26 mg single, oral dose: 26 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
496.23 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
52 mg single, oral dose: 52 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
1442.41 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
104 mg single, oral dose: 104 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
1261.85 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
148 mg single, oral dose: 148 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
2620.13 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
217 mg single, oral dose: 217 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
3517.77 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
348 mg single, oral dose: 348 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
5905.64 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
522 mg single, oral dose: 522 mg route of administration: Oral experiment type: SINGLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
6142.81 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
250 mg 2 times / day multiple, oral dose: 250 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
10379.9 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
300 mg 2 times / day multiple, oral dose: 300 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
14867.46 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
400 mg 2 times / day multiple, oral dose: 400 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
14216.41 ng × h/mL EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
500 mg 2 times / day multiple, oral dose: 500 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
T1/2
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
16.5 h EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/37712875/ |
500 mg 2 times / day multiple, oral dose: 500 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
CB-103 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Tue Apr 01 23:17:31 GMT 2025
by
admin
on
Tue Apr 01 23:17:31 GMT 2025
|
| Record UNII |
Q5BB91JL0V
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID00370659
Created by
admin on Tue Apr 01 23:17:31 GMT 2025 , Edited by admin on Tue Apr 01 23:17:31 GMT 2025
|
PRIMARY | |||
|
2735289
Created by
admin on Tue Apr 01 23:17:31 GMT 2025 , Edited by admin on Tue Apr 01 23:17:31 GMT 2025
|
PRIMARY | |||
|
300000035878
Created by
admin on Tue Apr 01 23:17:31 GMT 2025 , Edited by admin on Tue Apr 01 23:17:31 GMT 2025
|
PRIMARY | |||
|
DB15279
Created by
admin on Tue Apr 01 23:17:31 GMT 2025 , Edited by admin on Tue Apr 01 23:17:31 GMT 2025
|
PRIMARY | |||
|
Q5BB91JL0V
Created by
admin on Tue Apr 01 23:17:31 GMT 2025 , Edited by admin on Tue Apr 01 23:17:31 GMT 2025
|
PRIMARY | |||
|
218457-67-1
Created by
admin on Tue Apr 01 23:17:31 GMT 2025 , Edited by admin on Tue Apr 01 23:17:31 GMT 2025
|
PRIMARY | |||
|
12471
Created by
admin on Tue Apr 01 23:17:31 GMT 2025 , Edited by admin on Tue Apr 01 23:17:31 GMT 2025
|
PRIMARY | |||
|
C175580
Created by
admin on Tue Apr 01 23:17:31 GMT 2025 , Edited by admin on Tue Apr 01 23:17:31 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
SALT/SOLVATE -> PARENT |
|
||
|
TARGET -> INHIBITOR |
|
||
|
TARGET -> INHIBITOR |
|
||
|
TARGET -> INHIBITOR |
|
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ACTIVE MOIETY |
|
