Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C6H11NO2.ClH.H2O |
| Molecular Weight | 183.633 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
O.Cl.NC1(CCCC1)C(O)=O
InChI
InChIKey=REDNUMWNGCRGNH-UHFFFAOYSA-N
InChI=1S/C6H11NO2.ClH.H2O/c7-6(5(8)9)3-1-2-4-6;;/h1-4,7H2,(H,8,9);1H;1H2
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | H2O |
| Molecular Weight | 18.0153 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C6H11NO2 |
| Molecular Weight | 129.157 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S). | 2004-07 |
|
| NMDA receptor antagonism blocks the cardiovascular responses to microinjection of trans-ACPD into the NTS of awake rats. | 2004-05 |
|
| NMDA receptors in nucleus tractus solitarii are linked to soluble guanylate cyclase. | 2004-04 |
|
| Two helical conformations from a single foldamer backbone: "split personality" in short alpha/beta-peptides. | 2004-01-16 |
|
| Expression and functional properties of group I metabotropic glutamate receptors in bovine chromaffin cells. | 2004-01-15 |
|
| Glutamate-mediated cytosolic calcium oscillations regulate a pulsatile prostaglandin release from cultured rat astrocytes. | 2003-12-01 |
|
| Glutamate causes a loss in human cerebral endothelial barrier integrity through activation of NMDA receptor. | 2003-12 |
|
| Assessment of treatment response by autoradiography with (14)C-aminocyclopentane carboxylic acid, (67)Ga-DTPA, and (18)F-FDG in a herpes simplex virus thymidine kinase/ganciclovir brain tumor model. | 2003-11 |
|
| Structure of glutamate analogs that activate the ON bipolar cell metabotropic glutamate receptor in vertebrate retina. | 2003-10-23 |
|
| Alpha-cycloPNA: 1-aminocylopentane-1-carboxylic acid-derived peptide nucleic acid. | 2003-10-21 |
|
| Nicotine recruits a local glutamatergic circuit to excite septohippocampal GABAergic neurons. | 2003-09 |
|
| Hydroxyl radicals release in rat striatum involves metabotropic glutamate receptors. | 2003-08-30 |
|
| Characterization of S-adenosylmethionine synthetase in Cryptosporidium parvum (Apicomplexa). | 2003-08-29 |
|
| Functional synaptic contacts by intranuclear axon collaterals of thalamic relay neurons. | 2003-08-20 |
|
| Cooperativity between activation of metabotropic glutamate receptors and NMDA receptors in the induction of LTP in hippocampal CA1 neurons. | 2003-08 |
|
| Endogenous zinc as a retinal neuromodulator: evidence from the skate (Raja erinacea). | 2003-07-17 |
|
| Accommodation of alpha-substituted residues in the beta-peptide 12-helix: expanding the range of substitution patterns available to a foldamer scaffold. | 2003-07-16 |
|
| Expression of group I metabotropic glutamate receptors in rat hippocampal cells in culture and their characterization by intracellular calcium ion dynamics. | 2003-07 |
|
| Enhancement of low-voltage-activated calcium currents by group II metabotropic glutamate receptors in rat retinal ganglion cells. | 2003-07 |
|
| Characterisation of methionine adenosyltransferase from Mycobacterium smegmatis and M. tuberculosis. | 2003-06-16 |
|
| Peptide backbone folding induced by the C(alpha)-tetrasubstituted cyclic alpha-amino acids 4-amino-1,2-dithiolane-4-carboxylic acid (Adt) and 1-aminocyclopentane-1-carboxylic acid (Ac5c). A joint computational and experimental study. | 2003-06-07 |
|
| Synaptically activated Ca2+ waves in layer 2/3 and layer 5 rat neocortical pyramidal neurons. | 2003-06-01 |
|
| The role of ionotropic receptors of glutaminic acid in cardiovascular system. A. The influence of ionotropic receptor NMDA agonist - 1R,3R-ACPD and antagonist - DL-AP7 on the systemic pressure in rats. | 2003-06 |
|
| S-adenosylmethionine (AdoMet) modulates endotoxin stimulated interleukin-10 production in monocytes. | 2003-06 |
|
| Metabotropic glutamate receptors (mGluRs) are involved in early phase of memory formation: possible role of modulation of glutamate release. | 2003-05-14 |
|
| Glutamate receptors regulate Na/K-ATPase in cerebellum neurons. | 2003-04 |
|
| Carbon monoxide mediates vasodilator effects of glutamate in isolated pressurized cerebral arterioles of newborn pigs. | 2003-04 |
|
| Translation of clock rhythmicity into neural firing in suprachiasmatic nucleus requires mGluR-PLCbeta4 signaling. | 2003-04 |
|
| Activation of Ih is necessary for patterning of mGluR and mAChR induced network activity in the hippocampal CA3 region. | 2003-03 |
|
| The use of enantiomerically pure ketene dithioacetal bis(sulfoxides) in highly diastereoselective intramolecular nitrone cycloadditions. Application in the total synthesis of the beta-amino acid (-)-cispentacin and the first asymmetric synthesis of cis-(3R,4R)-4-amino-pyrrolidine-3-carboxylic acid. | 2003-02-21 |
|
| Antagonism of glutamatergic metabotropic receptors in the NTS of awake rats does not affect the gain of the baroreflex. | 2003-01-31 |
|
| Different roles of group I and group II metabotropic glutamate receptors on phencyclidine-induced dopamine release in the rat prefrontal cortex. | 2003-01-23 |
|
| Effects of calcium and glutamate receptor agonists on leaf consumption by lepidopteran neonates. | 2003-01 |
|
| Reduced activity of hippocampal group-I metabotropic glutamate receptors in learning-prone rats. | 2003 |
|
| Expression of angiogenic factors in hepatocellular carcinoma after transcatheter arterial chemoembolization. | 2003 |
|
| Effects of a selective metabotropic glutamate receptor agonist on the micturition reflex pathway in urethane-anesthetized rats. | 2003 |
|
| Dual modulation of gabaergic transmission by metabotropic glutamate receptors in rat ventral tegmental area. | 2003 |
|
| Actions of Group I and Group II metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission. | 2003 |
|
| A pharmacological analysis of the contractile effects of glutamate on rat and human isolated gut smooth muscle strips. | 2002-12 |
|
| Acamprosate inhibits the binding and neurotoxic effects of trans-ACPD, suggesting a novel site of action at metabotropic glutamate receptors. | 2002-12 |
|
| Cell type-selective expression of green fluorescent protein and the calcium indicating protein, yellow cameleon, in rat cortical primary cultures. | 2002-11-29 |
|
| Carbon monoxide and metabotropic glutamate receptors in rat nucleus tractus solitarii: participation in cardiovascular effect. | 2002-11-01 |
|
| Enantioselective synthesis of the excitatory amino acid (1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid. | 2002-11-01 |
|
| Synthesis and pharmacology of 3-hydroxy-delta2-isoxazoline-cyclopentane analogues of glutamic acid. | 2002-11 |
|
| A bicyclic cispentacin derivative as a novel reverse turn inducer in a GnRH mimetic. | 2002-10-04 |
|
| Group I metabotropic glutamate receptor-mediated enhancement of dopamine cell burst firing in rat ventral tegmental area in vitro. | 2002-09-06 |
|
| Spatial segregation and interaction of calcium signalling mechanisms in rat hippocampal CA1 pyramidal neurons. | 2002-09-01 |
|
| Activation of glutamate receptors inhibits Na/K-ATPase of cerebellum granule cells. | 2002-09 |
|
| Roles of ionotropic glutamate receptors in early developing neurons derived from the P19 mouse cell line. | 2002-06-19 |
|
| Glutamate induces different neuronal conditioned responses than ACPD when used as a locally ionophoresed unconditioned stimulus in the cat motor cortex. | 2002 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:15:46 GMT 2025
by
admin
on
Mon Mar 31 21:15:46 GMT 2025
|
| Record UNII |
Q54GQ146M2
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Common Name | English | ||
|
Preferred Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
Q54GQ146M2
Created by
admin on Mon Mar 31 21:15:46 GMT 2025 , Edited by admin on Mon Mar 31 21:15:46 GMT 2025
|
PRIMARY | |||
|
66146-62-1
Created by
admin on Mon Mar 31 21:15:46 GMT 2025 , Edited by admin on Mon Mar 31 21:15:46 GMT 2025
|
PRIMARY | |||
|
DTXSID30216334
Created by
admin on Mon Mar 31 21:15:46 GMT 2025 , Edited by admin on Mon Mar 31 21:15:46 GMT 2025
|
PRIMARY | |||
|
71369749
Created by
admin on Mon Mar 31 21:15:46 GMT 2025 , Edited by admin on Mon Mar 31 21:15:46 GMT 2025
|
PRIMARY | |||
|
m3997
Created by
admin on Mon Mar 31 21:15:46 GMT 2025 , Edited by admin on Mon Mar 31 21:15:46 GMT 2025
|
PRIMARY |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
ANHYDROUS->SOLVATE |
