U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 20:17:22 GMT 2025
Edited
by admin
on Wed Apr 02 20:17:22 GMT 2025
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State NON-REPLICATING GENETICALLY MODIFIED, SELF INACTIVATING
Organism Family Retroviridae
Organism Genus Lentivirus
Organism Species human immunodeficiency virus 1
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name LVV-EF-1?/CAR CD19 (scFv clone 1218)
Part whole
Record UNII
Q4SEW48YGM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Nespecabtagene autoleucel lentiviral vector
Common Name English
Nespecabtagene autoleucel lentiviral vector encoding CAR targeting CD19
Preferred Name English
Code System Code Type Description
FDA UNII
Q4SEW48YGM
Created by admin on Wed Apr 02 20:17:22 GMT 2025 , Edited by admin on Wed Apr 02 20:17:22 GMT 2025
PRIMARY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR UNSPECIFIED SUBSTANCE
28aee4c4
(not in database)