Ganipatide

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National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 12:51:22 GMT 2025` Edited by `admin` on `Wed Apr 02 12:51:22 GMT 2025`
Protein Type	PEPTIDE
Protein Sub Type
Sequence Origin	SYNTHETIC
Sequence Type	COMPLETE
Record UNII	Q47UHJ9U53
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-31-Glucose-dependent insulinotropic polypeptide (human NNC0480-0389), 1-(N-acetyl-D-tyrosine)-18-L-arginine-24-[N<sup>6</sup>-[N-[[trans-4-[[(19-carboxy-1-oxononadecyl)amino]methyl]cyclohexyl]carbonyl]-L-?-glutamyl-L-?-glutamyl-L-?-glutamyl]-L-lysine]-

Preferred Name

English

Ganipatide

Official Name

English

ganipatide [INN]

Common Name

English

N<sup>1</sup>-Acetyl-N<sup>6.24</sup>-({(1r,4r)-4-[(19-carboxynonadecanamido)methyl]cyclohexane-1-carbonyl}-L-?-glutamyl-L-?-glutamyl-L-?-glutamyl)[D-Tyr<sup>1</sup>,Aib<sup>2</sup>,Ahx<sup>14</sup>, Arg<sup>18</sup>,Lys<sup>24</sup>,Pro<sup>31</sup>]hum

Common Name

English

Code System Code Type Description

SMS_ID

300000051908

Created by admin on Wed Apr 02 12:51:22 GMT 2025 , Edited by admin on Wed Apr 02 12:51:22 GMT 2025

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NCI_THESAURUS

C203202

Created by admin on Wed Apr 02 12:51:22 GMT 2025 , Edited by admin on Wed Apr 02 12:51:22 GMT 2025

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INN

12745

Created by admin on Wed Apr 02 12:51:22 GMT 2025 , Edited by admin on Wed Apr 02 12:51:22 GMT 2025

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FDA UNII

Q47UHJ9U53

Created by admin on Wed Apr 02 12:51:22 GMT 2025 , Edited by admin on Wed Apr 02 12:51:22 GMT 2025

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CAS

2758595-29-6

Created by admin on Wed Apr 02 12:51:22 GMT 2025 , Edited by admin on Wed Apr 02 12:51:22 GMT 2025

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Related Record Type Details


					D6H00MV7K8

GASTRIC INHIBITORY POLYPEPTIDE RECEPTOR

TARGET -> AGONIST

Amount:

Related Record Type Details


					Q47UHJ9U53

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_24]	SITE_SPECIFIC		Amount:	UNSPECIFIED SUBSTANCE	21231d12 (not in database)
AMINO_ACID_SUBSTITUTION	[1_31]	SITE_SPECIFIC		Amount:	PROLINAMIDE	VD6PQK9DHG
AMINO_ACID_SUBSTITUTION	[1_1]	SITE_SPECIFIC		Amount:	N-ACETYL-D-TYROSINE	ZF9BXD0KPH
AMINO_ACID_SUBSTITUTION	[1_14]	SITE_SPECIFIC		Amount:	NORLEUCINE	832C8OV84S
AMINO_ACID_SUBSTITUTION	[1_2]	SITE_SPECIFIC		Amount:	.ALPHA.-AMINOISOBUTYRIC ACID	1E7ZW41IQU

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL