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Details

Stereochemistry ACHIRAL
Molecular Formula C18H37N.FH
Molecular Weight 287.4994
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of DECTAFLUR

SMILES

F.CCCCCCCC\C=C/CCCCCCCCN

InChI

InChIKey=QGSCPWWHMSCFOV-KVVVOXFISA-N
InChI=1S/C18H37N.FH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19;/h9-10H,2-8,11-19H2,1H3;1H/b10-9-;

HIDE SMILES / InChI

Molecular Formula C18H37N
Molecular Weight 267.4931
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Molecular Formula FH
Molecular Weight 20.0063
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description
Curator's Comment: description was created based on several sources, including https://www.drugs.com/international/olaflur.html | https://www.ncbi.nlm.nih.gov/pubmed/15528912 | https://clinicaltrials.gov/ct2/show/record/NCT00268138 | https://www.old.health.gov.il/units/pharmacy/trufot/alonim/4872.pdf

Oleylamine (or oleamine) is a versatile and flexible reagent in synthesis as well as the desired surface ligand for the synthesis of nanoparticles. This compound is rather toxic to mammalian organism.

CNS Activity

Originator

Sources: Helvetica Odontologica Acta (1962), 6, (1), 15-20.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Preventing
elmex

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
Epidemiology of 377 patients with chemical burns in Guangdong province.
2004 Sep
Sensitivity of human dental pulp cells to eighteen chemical agents used for endodontic treatments in dentistry.
2013 Jan
Allergic contact cheilitis caused by olaflur in toothpaste.
2017 Jan
Patents

Patents

Sample Use Guides

Brushing your teeth thoroughly with the preparation once a week. Just use elmex dental gel using a regular toothbrush for a period of 2-3 minutes, rinse normally. The total time of application (brushing and residence time) should not exceed five minutes.
Route of Administration: Dental
In Vitro Use Guide
The outer 50-100 mkm of the surface of freshly extracted human incisors was removed by grinding and polishing, thus removing not only the pellicle from the surface but also the outer mineral layer, which in general shows the greatest variation in chemical constituents. Amine fluoride 297 (AmF 297) were dissolved in distilled water. After adsorption of aminefluorides on the enamel for 2 min at a volume to area ratio of 25 cm3/cm2, the enamel surfaces were rinsed with distilled water and allowed to dry for several hours at room temperature in an enclosed chamber. Subsequently adsorbed layer thicknesses were determined by ellipsometry, and surface free energies were calculated from contact angle data.
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:03:00 GMT 2023
Edited
by admin
on Fri Dec 15 16:03:00 GMT 2023
Record UNII
Q3B1Y93C1S
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DECTAFLUR
INN   MART.   USAN   WHO-DD  
INN   USAN  
Official Name English
SK&F 38094
Code English
Dectaflur [WHO-DD]
Common Name English
9-Octadecenylamine hydrofluoride
Systematic Name English
9Z-OCTADECENYLAMINE HYDROFLUORIDE
Common Name English
dectaflur [INN]
Common Name English
SK&F-38094
Code English
DECTAFLUR [USAN]
Common Name English
OLEYL AMINE HYDROFLUORIDE
Systematic Name English
DECTAFLUR [MART.]
Common Name English
9-OCTADECEN-1-AMINE, HYDROFLUORIDE (1:1), (9Z)-
Common Name English
OLEYLAMINE HYDROFLUORIDE
Systematic Name English
Classification Tree Code System Code
NCI_THESAURUS C26170
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
Code System Code Type Description
NCI_THESAURUS
C83656
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
PRIMARY
FDA UNII
Q3B1Y93C1S
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
PRIMARY
CAS
7333-84-8
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
PRIMARY
MESH
C008703
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
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WIKIPEDIA
Dectaflur
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
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SMS_ID
100000083475
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
PRIMARY
CAS
36505-83-6
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
NON-SPECIFIC STEREOCHEMISTRY
EPA CompTox
DTXSID7073484
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
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PUBCHEM
20838116
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
PRIMARY
EVMPD
SUB06939MIG
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
PRIMARY
ChEMBL
CHEMBL2110897
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
PRIMARY
INN
3373
Created by admin on Fri Dec 15 16:03:00 GMT 2023 , Edited by admin on Fri Dec 15 16:03:00 GMT 2023
PRIMARY
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